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NCT06328088

Vegetarian Versus Non Vegetarian Based Diet in the Recurrence of Hepatic Encephalopathy in Patients With Cirrhosis: An Open Label Pilot Study

Status unknown Last updated 25 March 2024
What this trial tests

trial testing Non vegetarian in Hepatic Encephalopathy in 40 participants. Status unknown.

Timeline
16 February 2024
Primary endpoint
16 April 2024
16 October 2024

Quick facts

Lead sponsorSir Ganga Ram Hospital
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment40
Start date16 February 2024
Primary completion16 April 2024
Estimated completion16 October 2024
Sites1 location across India

Drugs / interventions tested

Conditions studied

Sponsor

Sir Ganga Ram Hospital

Who can join

Adults 18 to 80, any sex, with Hepatic Encephalopathy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Earlier protein restriction was advocated in the treatment of HE but later this concept was refuted and increase protein intake was advocated in patients with HE. Diet in patients during an episode HE is also not known. It is advisable based on many case reports or case series that vegetable-based diet during the episode of HE is better than animal-based diet as it reduces ammonia level and other false neurotransmitters in brain and helps in early recovery of, HE . However, diet in patients who had recovered from an episode of, HE is not known and what type of protein (vegetarian or non-vegetarian) should be taken to prevent another episode of HE has never been evaluated. In India majority of the patients are vegetarian and patients with cirrhosis are malnourished and lack protein in their diet as per our previous published study

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. The future of clinical trials of gut microbiome therapeutics in cirrhosis.
    Bloom PP, Chung RT. · · 2025 · cited 4× · PMID 39717506 · DOI 10.1016/j.jhepr.2024.101234

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Other recruiting trials for Hepatic Encephalopathy

Currently open trials in the same condition.

Other Sir Ganga Ram Hospital trials

Trials by the same sponsor.

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Data sources for this page

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