Last reviewed · How we verify
NCT06321549
New Era of DIEP With Minimally Invasive Mastectomy
trial testing The reference point of minimally invasive mastectomy procedure conducted in Breast Reconstruction in 278 participants. Completed in 2 October 2023.
2 October 2023
Quick facts
| Lead sponsor | Chang Gung Memorial Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 278 |
| Start date | 3 October 2022 |
| Primary completion | 2 October 2023 |
| Estimated completion | 2 October 2023 |
| Sites | 1 location across Taiwan |
Drugs / interventions tested
- The reference point of minimally invasive mastectomy procedure conducted
Conditions studied
- Breast Reconstruction — all drugs for Breast Reconstruction →
- Mastectomy; Lymphedema — all drugs for Mastectomy; Lymphedema →
Sponsor
Chang Gung Memorial Hospital
Who can join
Eligibility, female only, with Breast Reconstruction or Mastectomy; Lymphedema. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The free deep inferior epigastric artery perforator (DIEP) flap is the gold standard in autologous breast reconstruction. Asian patients often present with a smaller body mass index with relatively insufficient tissue. To restore appropriate symmetry, a larger flap inset ratio must be transferred. Supercharging of the second vein or inclusion of bilateral pedicle is commonly required. Current paradigm shifts in mastectomy has also resulted in more minimally invasive surgeries (MIS) espousing smaller lateral incisions, leading to a significant change in available recipient vessels. This study aimed to demonstrate our experience in changing strategies of DIEP flaps following the evolution of mastectomy techniques. Between October 2008 and March 2022, retrospective data was gathered for 278 patients who underwent breast reconstruction surgery utilizing DIEP flaps by a single plastic surgeon. These patients were divided into two distinct groups based on their operation dates, with November 2018 marking a pivotal moment when the first MIS was introduced.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Strategically shifting paradigms: the new era of DIEP flaps with minimally invasive mastectomy: a retrospective cross-sectional study.
Lin TE, Wong AW, Cheong DC, Kuo WL, et al · · 2024 · cited 2× · PMID 39210299 · DOI 10.1186/s12885-024-12846-x
Verify or expand the search:
- PubMed search for NCT06321549
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Breast Reconstruction
Currently open trials in the same condition.
- NCT07230535 — Evaluation of Wellbeing and Patient Reported Outcomes After Open vs Robotic Mastectomy With DIEP Reconstruction · NA · recruiting
- NCT07293052 — Comparison of Outcome Between Grisotti Flap Versus Reverse Mirror Grisotti Flap for Central Quadrant Breast Tumors · NA · active not recruiting
- NCT07331753 — The Outcomes of Fat Grafting Combined With Latissimus Dorsi Muscle Flap for Delayed Breast Reconstruction After Mastecto · NA · recruiting
- NCT07185334 — Single-Stage Prepectoral Placement of Textured Implants Using a Polyester Mesh Endoprostheses With Fluoropolymer Coating · NA · active not recruiting
- NCT06993714 — 3D-printed Biodegradable Breast Implants for Breast Restoration · Phase 2 · recruiting
Other Chang Gung Memorial Hospital trials
Trials by the same sponsor.
- NCT07419789 — Precision Care for Older Persons · NA · not yet recruiting
- NCT07248345 — Virtual Reality Intervention for Family Caregivers of Persons Living With Dementia · NA · not yet recruiting
- NCT07036978 — Metabolomic and Immune-Microbiome Profiling for Unresectable Pancreatic Cancer · not yet recruiting
- NCT07489833 — Metabolomic Pathways and Traditional Chinese Medicine Body Constitution in Cancer-related Fatigue · not yet recruiting
- NCT07496528 — The ACURE Trial: Acupuncture for Colorectal Recovery · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06321549 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Chang Gung Memorial Hospital
- Last refreshed: 20 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06321549.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing