Last reviewed · How we verify
NCT06316752
The Natural History of Sialidosis Type I
trial testing Observational study in Observational Study in 30 participants. Currently enrolling.
16 December 2026
Quick facts
| Lead sponsor | National Taiwan University Hospital |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 30 |
| Start date | 15 March 2022 |
| Primary completion | 16 December 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across Taiwan |
Drugs / interventions tested
- Observational study — full drug profile →
Conditions studied
- Observational Study — all drugs for Observational Study →
Sponsor
National Taiwan University Hospital
Who can join
Adults 12 to 80, any sex, with Observational Study. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Sialidosis type 1 is an autosomal recessive disorder caused by bialleic NEU1 gene mutations. Patients with sialidosis type I present variable neurological and eye dysfunction and the progression rate is variable. The goal of this protocol is to assess the neurological and ophthalmological status of these patients and characterize the clinical and laboratory abnormalities in order to determine the natural history of the disease. Patients will be followed every 6 month with comprehensive clinical, neurological and ophthalmological examinations combined with neuropsychological, blood, radiological and electrophysiological tests.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Sialidosis type I: How to alleviate disabling myoclonic seizures?-A multicenter analysis of eight cases and review of the literature.
Gburek-Augustat J, Lee IC, Rubino M, Topçu V, et al · · 2026 · PMID 41665440 · DOI 10.1002/epi4.70233
Verify or expand the search:
- PubMed search for NCT06316752
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Observational study
Trials testing the same drug.
- NCT07255443 — Intestinal Colonization With Carbapenem Resistant Enterobacteriaceae Among ICU Patients at Assiut University Hospital · not yet recruiting
- NCT07343713 — Correlation Between the Degree of Middle Ear Pressure and the Eustachian Tube Dimensions : Radiological Study · not yet recruiting
- NCT07192991 — Neuroendocrine Carcinomas: Patient Journey And Treatment Outcomes In Latin America · not yet recruiting
- NCT07219927 — Real-World Patient Experiences Using Continuous Subcutaneous Apomorphine Infusion (ONAPGOTM) in the United States: · recruiting
- NCT06244238 — A Study on the Relationship Between Job Satisfaction and Retention Intentions of Emergency Room Nurses · unknown
Other recruiting trials for Observational Study
Currently open trials in the same condition.
- NCT07374614 — Iruplinalkib in ALK-Positive Advanced Lung Adenocarcinoma After Lorlatinib · recruiting
- NCT07117227 — Validation of RCC Predicting Model With Emulated-target Trial · recruiting
- NCT07072741 — Assessing the Feasibility and Acceptability of Watching Queen of Katwe as a Role Model Intervention Among Adolescents in · NA · recruiting
- NCT07089914 — Health Surveillance at University of Applied Science Hamburg (HAW) · active not recruiting
- NCT07424872 — Project VERANDA: Requirement Analysis Survey · recruiting
Other National Taiwan University Hospital trials
Trials by the same sponsor.
- NCT06936917 — Timing for Computed Tomography and Post-Resuscitation Care on Short-Term Outcomes in Out-of-Hospital Cardiac Arrest · not yet recruiting
- NCT05396222 — A Prospective Study of the Safety and Efficacy of 3D-printed Non-rigid Biomimetic Implant in Cervical and Thoracolumbar · NA · not yet recruiting
- NCT07532356 — Integrating Tumor Genomics and Urinary Exosomal Proteomics to Establish a Multi-Layer Biomarker Framework for Early Risk · not yet recruiting
- NCT07317310 — The NTU JO-SMART Study · NA · not yet recruiting
- NCT07382024 — Tirzepatide to Reduce rEcurrence And Burden After Ablation of Atrial Fibrillation · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06316752 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Taiwan University Hospital
- Last refreshed: 20 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06316752.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing