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NCT06316557: HOPE
HOPE From the Cerebellum: TMS-Induced Cognitive Recovery After Stroke
NA trial testing iTBS group in Post-stroke Cognitive Impairment in 70 participants. Currently enrolling.
1 July 2026
Quick facts
| Lead sponsor | Zi-Xiao Li |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 70 |
| Start date | 1 January 2025 |
| Primary completion | 1 July 2026 |
| Estimated completion | 1 April 2027 |
| Sites | 1 location across China |
Drugs / interventions tested
- iTBS group
- control group — full drug profile →
Conditions studied
- Post-stroke Cognitive Impairment — all drugs for Post-stroke Cognitive Impairment →
- Ischemic Stroke — all drugs for Ischemic Stroke →
Sponsor
Zi-Xiao Li
Who can join
18 and older, any sex, with Post-stroke Cognitive Impairment or Ischemic Stroke. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objective of this clinical trial is to investigate the effectiveness and safety of repetitive transcranial magnetic stimulation (rTMS) in the cerebellum for individuals with post-stroke cognitive impairment. Participants will undergo rTMS in the cerebellar hemisphere opposite the lesion site, once daily for a total of five days.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06316557
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Post-stroke Cognitive Impairment
Currently open trials in the same condition.
- NCT06315231 — Edaravone Dexborneol Sublingual Tablet for the PSCI in Acute Ischemic Stroke Patients · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06316557 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Zi-Xiao Li
- Last refreshed: 2 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06316557.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing