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NCT06314737
Assessment of Efficacy of Neoadjuvant Therapy in Locally Advanced Rectal Cancer
trial in Locally Advanced Rectal Carcinoma in 3,515 participants. Completed in 1 January 2024.
6 December 2018
Quick facts
| Lead sponsor | Sixth Affiliated Hospital, Sun Yat-sen University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 3,515 |
| Start date | 2 October 2010 |
| Primary completion | 6 December 2018 |
| Estimated completion | 1 January 2024 |
Conditions studied
- Locally Advanced Rectal Carcinoma — all drugs for Locally Advanced Rectal Carcinoma →
Sponsor
Sixth Affiliated Hospital, Sun Yat-sen University
Who can join
Eligibility, any sex, with Locally Advanced Rectal Carcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study analyzed the efficacy differences between neoadjuvant therapy and direct surgical treatment in patients with locally advanced rectal cancer in the real world. The aim was to evaluate the impact of neoadjuvant therapy on overall survival, disease-free survival, and local recurrence-free survival in patients with locally advanced rectal cancer, explore the population benefiting most from neoadjuvant therapy, and provide evidence-based medicine for the benefits of neoadjuvant therapy in patients with colorectal cancer in the real world.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Does the initial treatment of primary tumor impact prognosis after recurrence in locally advanced rectal cancer? Results from a retrospective cohort analysis.
Wang Z, Bai F, Chen Y, Liu X, et al · · 2024 · PMID 39333450 · DOI 10.1007/s00384-024-04721-9 -
Does the Initial Treatment of the Primary Tumor Impact Prognosis after Recurrence in Locally Advanced Rectal Cancer? Results From A Retrospective Cohort Analysis
Wang Z, Bai F, Chen Y, Liu X, et al · · 2024 · DOI 10.21203/rs.3.rs-4680948/v1
Verify or expand the search:
- PubMed search for NCT06314737
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Locally Advanced Rectal Carcinoma
Currently open trials in the same condition.
- NCT07372300 — Modulated Electro-Hyperthermia in Combination With Multimodal Therapy for Locally Advanced Rectal Cancer · Phase 3 · recruiting
- NCT07038122 — Reducing the Resection Range After Neoadjuvant Therapy for Locally Advanced Upper Rectal and Rectosigmoid Junction Cance · NA · active not recruiting
- NCT06276686 — Exercise for Improving Long-course Chemoradiotherapy Efficacy in People With Locally Advanced Rectal Cancer · EARLY_PHASE1 · recruiting
- NCT06312982 — A Series of Neoadjuvant Chemoradiotherapy Combined With Immunotherapy for Locally Advanced Rectal Cancer · Phase 2, PHASE3 · recruiting
- NCT05731726 — Serplulimab Combined With CAPEOX + Celecoxib as Neoadjuvant Treatment for Locally Advanced Rectal Cancer · Phase 2 · recruiting
Other Sixth Affiliated Hospital, Sun Yat-sen University trials
Trials by the same sponsor.
- NCT07538284 — MInimizing Delirium With Nasal Dexmedetomidine-InducEd Sleep (MIDDIES) · Phase 2, PHASE3 · not yet recruiting
- NCT07176182 — Clinical Trial of Neoadjuvant mFOLFOX Plus Alvenor for LARC Patients With High YWHAB Expression · Phase 2 · not yet recruiting
- NCT07510191 — TNFi Plus Low-Dose Upadacitinib vs TNFi Intensification in Crohn's Disease With Suboptimal Response · Phase 4 · recruiting
- NCT07344428 — Efficacy and Safety of CDED With Anti-TNF-α Biologics in Crohn's Disease: A Randomized Trial · NA · not yet recruiting
- NCT07328958 — Effect of Titrated Administration of Ciprofol on Perioperative Hypotension in Elderly Patients Undergoing Laparoscopic A · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06314737 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sixth Affiliated Hospital, Sun Yat-sen University
- Last refreshed: 18 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06314737.
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