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NCT06312436: AT-REBOA
The AT-REBOA Target Trial
trial testing Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) in Hemorrhage in 44 participants. Completed in 20 December 2024.
1 October 2023
Quick facts
| Lead sponsor | Medical University of Graz |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 44 |
| Start date | 1 January 2019 |
| Primary completion | 1 October 2023 |
| Estimated completion | 20 December 2024 |
| Sites | 2 locations across Austria |
Drugs / interventions tested
- Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA)
Conditions studied
- Hemorrhage — all drugs for Hemorrhage →
- Shock, Traumatic — all drugs for Shock, Traumatic →
- Cardiac Arrest Due to Trauma — all drugs for Cardiac Arrest Due to Trauma →
- Polytrauma — all drugs for Polytrauma →
Sponsor
Medical University of Graz
Who can join
16 and older, any sex, with Hemorrhage or Shock, Traumatic. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Temporary aortic occlusion can limit haemorrhage, can help to maintain perfusion to the heart and brain, and may be associated with improved survival. Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) potentially provides a relatively quick means of achieving this temporary control. In the past years, studies have tried to evaluate the benefit for this method with conflicting results. The previous UK-REBOA trial has not found any benefit in the intervention group and has even hinted at possible harm caused by the intervention. A major limitation of this study is the low number of interventions performed in participating trauma centres and the associated potentially insufficient experience with REBOA. The aim of this study is to evaluate the effectiveness of REBOA in a setting with already experienced providers.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
REBOA: A novel life-saving tool for non-compressible traumatic hemorrhage.
Hu W, Tian X, Li X, Liu F. · · 2024 · cited 1× · PMID 39101488 · DOI 10.1097/cm9.0000000000003243
Verify or expand the search:
- PubMed search for NCT06312436
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA)
Trials testing the same drug.
- NCT04145271 — Pre-Hospital Zone 1 Partial Resuscitative Endovascular Balloon Occlusion of the Aorta for Injured Patients With Exsangui · completed
Other recruiting trials for Hemorrhage
Currently open trials in the same condition.
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Other Medical University of Graz trials
Trials by the same sponsor.
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- NCT07492823 — Clinical Applicability of Liquid Biopsy in Chondrosarcoma · not yet recruiting
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- NCT07588282 — The Effect of Psychoeducational Diagnosis Communication on Perception of Illness, Satisfaction, and Behavioral Intention · NA · recruiting
- NCT07376096 — Liquid Biopsy in Germ Cell Tumors · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06312436 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Medical University of Graz
- Last refreshed: 22 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06312436.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing