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NCT06311617
Understanding Retinal Vascular Changes During Pregnancy and the Impact on Maternal and Fetal Health
trial testing Optical coherence tomography in Pregnancy in 90 participants. Currently enrolling.
1 January 2027
Quick facts
| Lead sponsor | Vanderbilt University Medical Center |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 90 |
| Start date | 1 February 2024 |
| Primary completion | 1 January 2027 |
| Estimated completion | 1 January 2027 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Optical coherence tomography
Conditions studied
- Pregnancy — all drugs for Pregnancy →
Sponsor
Vanderbilt University Medical Center
Who can join
18 and older, female only, with Pregnancy.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Imaging Biomarkers: Choroid
Time frame: during 9 months of pregnancy and in the 3 months after pregnancy
Choroidal thickness -
Imaging Biomarkers: Vessel density
Time frame: during 9 months of pregnancy and in the 3 months after pregnancy
Vessel density -
Imaging Biomarkers: Foveal avascular zone (FAZ)
Time frame: during 9 months of pregnancy and in the 3 months after pregnancy
FAZ area
Sponsor's own description
The goal of this study is to better understand how the back part of the eye-called the retina and the choroid-changes during pregnancy. Specialized photos of the eye will be taken at three different timepoints: early in pregnancy (first or second trimester), late in pregnancy (third trimester), and after delivery. This imaging is non-invasive and does not require contact with the surface of the eye. The photos taken will allow assessment of specific parameters, like blood flow and the health of specialized cells that support vision. Understanding how the eyes change during pregnancy may help guide how retina specialists understanding of retinal disease during pregnancy and better inform pregnancy outcomes.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06311617
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06311617 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Vanderbilt University Medical Center
- Last refreshed: 4 May 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06311617.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing