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NCT06311058
Protein Supplementation After ACL Surgery
NA trial testing Whey protein isolate in ACL Reconstruction in 102 participants. Currently enrolling.
1 December 2026
Quick facts
| Lead sponsor | The Methodist Hospital Research Institute |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | supportive care |
| Enrollment | 102 |
| Start date | 16 February 2024 |
| Primary completion | 1 December 2026 |
| Estimated completion | 1 December 2027 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Whey protein isolate
- Protein + BAA
- Placebo
Conditions studied
- ACL Reconstruction — all drugs for ACL Reconstruction →
Sponsor
The Methodist Hospital Research Institute
Who can join
Adults 16 to 40, any sex, with ACL Reconstruction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of the study is to assess the longitudinal post-operative care effects of protein supplementation on muscle atrophy in the post-operative period following ACL reconstruction. The main outcome will be muscle size/mass as measured using dual energy x-ray absorptiometry (DEXA) scanning. The primary objective is to assess for any beneficial impact of protein supplementation, with implications of standardizing a recommended protocol for protein supplementation after ACL reconstruction. Secondary outcomes will be to evaluate the survey data from the KOOS JR and Tampa Scale surveys, as well as functional measures recorded during physical therapy.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06311058
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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- NCT04864769 — Effect of Intake of Hydrolyzed Krill Protein Isolate on Plasma Amino Acid Profile · NA · completed
- NCT05112146 — Effects of Whey Protein Pre-meals on Post-prandial Glucose · NA · completed
Other recruiting trials for ACL Reconstruction
Currently open trials in the same condition.
- NCT07470359 — Comparison of Functional Outcomes Following Arthroscopic ACL Reconstruction With Peroneus Longus Autograft With and With · Phase 2 · recruiting
- NCT07190456 — Kinesiophobia vs. Task-Specific Fear: Defining Movement-Related Fear in ACL Reconstruction Patients · NA · recruiting
- NCT06748066 — Developing and Validating the Risk-taking Intention and Sport Engagement After ACL Reconstruction (RISE-ACL) Scale · NA · active not recruiting
- NCT06688344 — Efficacy of Focused Extracorporeal Shock Wave Therapy After Anterior Cruciate Ligament Reconstruction · NA · recruiting
- NCT06979804 — A Comparison of Outcomes After Anterior Cruciate Ligament (ACL) or Anterior Cruciate Ligament and Meniscus (ACL+Meniscus · NA · recruiting
Other The Methodist Hospital Research Institute trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06311058 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The Methodist Hospital Research Institute
- Last refreshed: 6 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06311058.
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