NCT06305000 is a NA clinical trial of Non-surgical treatment in Peri-implant Mucositis, sponsored by Biruni University.

Who is sponsoring NCT06305000?

NCT06305000 is sponsored by Biruni University.

What drugs are being tested in NCT06305000?

Interventions in NCT06305000: Non-surgical treatment, Free gingival graft.

What condition does NCT06305000 study?

NCT06305000 studies Peri-implant Mucositis.

Is NCT06305000 still recruiting?

NCT06305000 is currently recruiting now. Last updated 10 February 2026.

Last reviewed 2026-02-10 · How we verify

NCT06305000

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Impact of Keratinized Mucosa Augmentation on Treatment Outcomes of Peri-implant Mucositis

Recruiting now NA Last updated 10 February 2026

What this trial tests

NA trial testing Non-surgical treatment in Peri-implant Mucositis in 48 participants. Currently enrolling.

Timeline

27 March 2024

Primary endpoint
10 September 2026

10 September 2026

Quick facts

Lead sponsor	Biruni University
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	48
Start date	27 March 2024
Primary completion	10 September 2026
Estimated completion	10 September 2026
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

Non-surgical treatment
Free gingival graft

Conditions studied

Peri-implant Mucositis — all drugs for Peri-implant Mucositis →

Sponsor

Biruni University

Who can join

18 and older, any sex, with Peri-implant Mucositis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aims to observe the effects of keratinized mucosa width on peri-implant tissues by evaluating clinical and biochemical parameters. The main question it aims to answer is: Would increasing the width of the keratinized mucosa with free gingival graft (FGG) in peri-implant mucositis be beneficial in terms of clinical periodontal parameters and peri-implant crevicular fluid levels of inflammatory cytokines compared to non-surgical therapy alone? Our study consists of 4 groups: Peri-implant healthy group with sufficient keratinized mucosa (≥ 2mm) (n=16), peri-implant mucositis group with sufficient keratinized mucosa (n=16), peri-implant mucositis group with insufficient keratinized mucosa (\< 2mm) receiving only non-surgical treatment (n=16), peri-implant mucositis group with insufficient keratinized mucosa receiving FGG in addition to non-surgical treatment (n=16). Clinical and biochemical measurements will be recorded at the baseline, 1st month, 4th month and 7th month of the study. Peri-implant crevicular fluid samples will be collected at baseline, 1st month, 4th month and 7th month. IL-1β, RANKL, OPG levels, and RANKL/OPG ratio will be analyzed from collected samples. Researchers will evaluate the possible benefits of FGG application in addition to non-surgical therapy by comparing the biochemical and clinical changes in areas with and without FGG application in the treatment of peri-implant mucositis.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Non-surgical treatment

Trials testing the same drug.

NCT04574336 — Scandinavian Humeral Diaphyseal Fracture Trial · NA · recruiting
NCT04420832 — Acute Achilles Tendon Rupture - Choice of Treatment Based on Ultrasound Findings · NA · active not recruiting
NCT05315466 — Comparison Between Surgical and Conservative Treatment for Lumbar Stenosis · NA · completed

Other recruiting trials for Peri-implant Mucositis

Currently open trials in the same condition.

NCT07349095 — AI-Assisted Colorimetric Diagnosis of Peri-Implant Mucosal Erythema · NA · recruiting
NCT07140146 — Trehalose vs Glycine Air-Polishing in Peri-Implant Mucositis Treatment · NA · recruiting
NCT06645444 — Immediate Implant Placement With Different Materials of Customized Healing Abutment for Guiding Peri-implant Soft Tissue · NA · recruiting
NCT07047261 — Efficacy of a Xanthan-based Chlorhexidine Gel in the Treatment of Peri-implant Mucositis · NA · recruiting
NCT06364982 — Distance Between Dental Implants as a Risk Indicator for Peri-implant Disease. · recruiting

Other Biruni University trials

Trials by the same sponsor.

NCT07509762 — Exercise Programs in Women With PCOS · NA · not yet recruiting
NCT07499843 — Synchronous vs. Asynchronous Telerehabilitation for High-Risk Infants · NA · not yet recruiting
NCT07495540 — Comparison of the Effects of Free Weight and Machine-Based Exercises on Muscular Parameters · NA · not yet recruiting
NCT07452328 — Postural Stability and Trunk Strength in Wrestlers · not yet recruiting
NCT07467525 — Neuromuscular Effects of Acute Fatigue in Adolescent Basketball · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06305000 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Biruni University
Last refreshed: 10 February 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06305000.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing