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NCT06303960
Cerebellar Deep Brain Stimulation or VNS for Chronic Post-stroke Motor Rehabilitation
EARLY_PHASE1 trial testing Bilateral Cerebellar deep brain stimulation in Stroke in 100 participants. Currently enrolling.
7 June 2025
Quick facts
| Lead sponsor | Qilu Hospital of Shandong University |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 100 |
| Start date | 15 March 2024 |
| Primary completion | 7 June 2025 |
| Estimated completion | 7 March 2026 |
| Sites | 1 location across China |
Drugs / interventions tested
- Bilateral Cerebellar deep brain stimulation
- Unilateral Cerebellar deep brain stimulation
- Vagus Nerve Stimulation
Conditions studied
- Stroke — all drugs for Stroke →
Sponsor
Qilu Hospital of Shandong University
Who can join
Adults 30 to 75, any sex, with Stroke. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Upper-extremity impairment after stroke remains a major therapeutic challenge and a target of neuromodulation treatment efforts.In this open-label, randomized phase I trial, we applied deep brain stimulation to the cerebellar dentate nucleus combined with bilateral or unilateral stimulation. Vagus nerve stimulation was also conducted for motor function after ischaemic Stroke.We hypothesized that cerebellar stimulation was superior to vagus stimulation as the motor rehabilitation after stroke benefits from both side of cerebellum.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06303960
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Qilu Hospital of Shandong University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06303960 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Qilu Hospital of Shandong University
- Last refreshed: 17 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06303960.
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