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NCT06300788: PPi-DIA
Inorganic Pyrophosphate Homeostasis (PPi) in Pediatric Chronic Kidney Disease
NA trial testing PPI and T50 dosing in Pyrophosphate, Fetuin A, IL1, IL6, TNFalpha, Control in 60 participants. Currently enrolling.
27 November 2026
Quick facts
| Lead sponsor | Centre Hospitalier Universitaire de Nice |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 60 |
| Start date | 27 May 2024 |
| Primary completion | 27 November 2026 |
| Estimated completion | 27 November 2026 |
| Sites | 1 location across France |
Drugs / interventions tested
- PPI and T50 dosing
Conditions studied
- Pyrophosphate, Fetuin A, IL1, IL6, TNFalpha, Control — all drugs for Pyrophosphate, Fetuin A, IL1, IL6, TNFalpha, Control →
Sponsor
Centre Hospitalier Universitaire de Nice
Who can join
Adults 0 to 18, any sex, with Pyrophosphate, Fetuin A, IL1, IL6, TNFalpha, Control. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigator aim to identify the role of inorganic pyrophosphate and other anti-calcifying molecules in vascular disease in children with chronic kidney disease, with a view to developing therapeutic approaches aimed at limiting the onset of vasculopathy.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06300788
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06300788 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire de Nice
- Last refreshed: 10 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06300788.
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