Last reviewed · How we verify
NCT06299930
Locoregional Recurrence After Neoadjuvant Versus Adjuvant Chemotherapy
trial testing Neoadjuvant chemotherapy in Breast Cancer in 10,328 participants. Completed in 12 September 2023.
16 August 2023
Quick facts
| Lead sponsor | Seoul National University Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 10,328 |
| Start date | 22 April 2022 |
| Primary completion | 16 August 2023 |
| Estimated completion | 12 September 2023 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- Neoadjuvant chemotherapy — full drug profile →
- Adjuvant chemotherapy — full drug profile →
Conditions studied
- Breast Cancer — all drugs for Breast Cancer →
Sponsor
Seoul National University Hospital
Who can join
Adults 18 to 100, female only, with Breast Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Neoadjuvant chemotherapy (NACT) for early-stage breast cancer is associated with an increased risk of locoregional recurrence (LRR). However, few studies have conducted subgroup analyses of patients with various molecular subtypes, which are one of the determinant factors for treatments. The aim of the study is to investigate whether the risk of LRR after NACT varies across tumor subtypes. The investigators retrospectively reviewed the medical records of female breast cancer patients who underwent breast-conserving surgery at three institutions between January 1, 2004, and Dec 31, 2018.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Locoregional recurrence after neoadjuvant versus adjuvant chemotherapy based on tumor subtypes in patients with early-stage breast cancer: A multi-institutional retrospective cohort study.
Cheun JH, Kwak Y, Kang E, Jung JJ, et al · · 2024 · cited 1× · PMID 39515238 · DOI 10.1016/j.breast.2024.103828
Verify or expand the search:
- PubMed search for NCT06299930
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06299930 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Seoul National University Hospital
- Last refreshed: 8 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06299930.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing