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NCT06299020

Risks of Intermittent Fasting in Patients With Primary Adrenal Insufficiency

Completed NA Last updated 14 February 2025
What this trial tests

NA trial testing intermittent fasting in Primary Adrenal Insufficiency in 30 participants. Completed in 1 December 2024.

Timeline
4 March 2024
Primary endpoint
20 April 2024
1 December 2024

Quick facts

Lead sponsorHopital La Rabta
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designcrossover
Maskingnone
Primary purposediagnostic
Enrollment30
Start date4 March 2024
Primary completion20 April 2024
Estimated completion1 December 2024
Sites1 location across Tunisia

Drugs / interventions tested

Conditions studied

Sponsor

Hopital La Rabta — full company profile →

Who can join

Adults 20 to 65, any sex, with Primary Adrenal Insufficiency or Intermittent Fasting. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In primary adrenal insufficiency, there is an increased risk of hypoglycaemia and dehydration. These risks have been little studied particularly during intermittent fasting. The present study aimed to assess these risks in a prospective study of 30 subjects with primary adrenal insufficiency. Patients will undergo a clinical examination, blood sampling and continuous glucose monitoring for fourteen days (one week of fasting and one week of non-fasting).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Hypoglycaemia and other risks of ramadan fasting in patients with primary adrenal insufficiency: A prospective controlled trial using 24-hour glucose monitoring.
    Chihaoui M, Sta J, Kamoun E, Belhadjsliman C, et al · · 2026 · PMID 41108503 · DOI 10.1007/s40618-025-02728-9

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