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NCT06297239: GAELpa

Argentine Registry of Lp(a)

Status unknown Last updated 7 March 2024
What this trial tests

trial in Lp(A) in 1,000 participants. Status unknown.

Timeline
1 February 2024
Primary endpoint
1 February 2026
1 February 2026

Quick facts

Lead sponsorSchool of Medicine. National University of Cuyo
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment1,000
Start date1 February 2024
Primary completion1 February 2026
Estimated completion1 February 2026
Sites1 location across Argentina

Conditions studied

Sponsor

School of Medicine. National University of Cuyo

Who can join

18 and older, any sex, with Lp(A) or Hypercholesterolemia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The Argentine Registry on Lipoprotein(a) (LP(a)), orchestrated by the Argentine Group for LP(a) Study, stands as a pioneering and extensive prospective initiative. This registry systematically collects geolocation data, including patient postal codes, demographic information, and a multifaceted array of health parameters to unravel the intricate associations surrounding LP(a) levels. The dataset encompasses diverse patient characteristics, ranging from standard metrics like blood pressure, weight, and race to broader factors such as diabetes, smoking habits, menopausal status, and hypothyroidism. This holistic approach enables a nuanced exploration of the interplay between LP(a) levels and various risk factors, providing invaluable insights for both clinical and public health considerations. One distinctive feature of this registry lies in its focus on medication history, shedding light on the impact of routine pharmaceutical interventions on LP(a) profiles. Additionally, it delves into the intricate web of inflammatory diseases, recognizing their potential role in LP(a) modulation. Genetic predispositions are meticulously examined, with a specific emphasis on identifying homozygous and heterozygous variants associated with hypercholesterolemia. This genetic dimension adds a layer of complexity to the understanding of LP(a) dynamics, contributing significantly to the ongoing discourse on cardiovascular risk. The prospective nature of this registry allows for dynamic analyses, fostering a continuous exploration of emerging patterns and trends. By amalgamating geographical, clinical, and genetic data, the Argentine LP(a) Registry emerges as a comprehensive platform poised to unlock novel facets of LP(a) biology and its implications for cardiovascular health. As the dataset matures, it holds the promise of guiding personalized interventions and refining risk stratification strategies, thereby advancing the landscape of preventive cardiovascular care.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other School of Medicine. National University of Cuyo trials

Trials by the same sponsor.

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Data sources for this page

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