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NCT06296576: ATACLI
Acceleration Time Assessment for Prediction of Critical Limb Ischemia
trial testing arterial ultrasound scan in Critical Limb Ischemia in 431 participants. Currently enrolling.
1 September 2026
Quick facts
| Lead sponsor | Centre Hospitalier le Mans |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 431 |
| Start date | 1 July 2024 |
| Primary completion | 1 September 2026 |
| Estimated completion | 1 September 2026 |
| Sites | 3 locations across France |
Drugs / interventions tested
- arterial ultrasound scan
Conditions studied
- Critical Limb Ischemia — all drugs for Critical Limb Ischemia →
Sponsor
Centre Hospitalier le Mans
Who can join
18 and older, any sex, with Critical Limb Ischemia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Critical Limb Ischaemia (CLI), the final stage of arterial disease, is a therapeutic emergency whose prognosis depends largely on the time taken to diagnose it. The growing prevalence of this condition and the associated healthcare costs make it an important public health objective. Diagnostic criteria for Critical Limb Ischaemia differ between learned societies and countries. Its diagnosis is most frequently based on the combination of a clinical criterion (ischaemic decubitus pain and/or necrotic wounds, with a time to onset \> 2 weeks) and a haemodynamic criterion (ankle systolic pressure (ASP) \< 50mmHg or toe systolic pressure (TSP) \< 30 mmHg or transcutaneous oxygen pressure (TCPO2) \< 30 mmHg). Recent studies have highlighted the importance of pulsed Doppler flow analysis in quantifying arteriopathy of the lower limbs, both by systematically analysing flow modulation and by measuring the systolic rise time of distal arteries (dorsal artery of the foot and lateral plantar artery). The main aim of this study is therefore to validate a reliable and accessible diagnostic tool for screening patients suffering from CLI so that they can be referred to a reference centre as early as possible.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06296576
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Critical Limb Ischemia
Currently open trials in the same condition.
- NCT04433572 — Temsirolimus Adventitial Delivery to Improve ANGioplasty and/or Atherectomy Revascularization Outcomes Below the Knee · Phase 3 · recruiting
- NCT06434194 — Serrantor OCT Study · NA · recruiting
- NCT06482892 — TP03HN106 in Patients With Critical Limb Ischemia · Phase 2 · recruiting
- NCT06075940 — Evaluation of the MAGNITUDE® Bioresorbable Drug-Eluting Scaffold in the Treatment of Patients With Below the Knee Diseas · NA · recruiting
- NCT06174597 — Umbilical Cord Artery-derived Perivascular Stem Cells for the Critical Limb Ischemia Therapy · EARLY_PHASE1 · recruiting
Other Centre Hospitalier le Mans trials
Trials by the same sponsor.
- NCT07365644 — Prophylactic ANTicoagulation With HEparine in Critically Ill Patients With Renal Impairment · not yet recruiting
- NCT07301957 — Impact of Early Rupture of the Residual Membrane on Latency Before Labour Begins · NA · not yet recruiting
- NCT07458477 — Digital Audiometer vs. Conventional Audiometer (Gold Standard): Study of Tonal and Vocal Recognition Thresholds · NA · recruiting
- NCT06799806 — The Impact of the Therapeutic Virtual Reality Headset on Patient Anxiety in the Waiting Room Before Flexible Bronchoscop · NA · recruiting
- NCT05915663 — Impact of the Choice of Gastric Tube Placement Sites on the Incidence of Ventilator Associated Pneumonia · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06296576 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier le Mans
- Last refreshed: 29 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06296576.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing