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NCT06295666
Gingival Crevicular Fluid (GCF) Bactericidal Permeability Protein (BPI) and Interleukin (IL)-1 Beta
trial in Periodontitis in 100 participants. Completed in 20 January 2020.
25 November 2019
Quick facts
| Lead sponsor | Akdeniz University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 19 February 2019 |
| Primary completion | 25 November 2019 |
| Estimated completion | 20 January 2020 |
| Sites | 1 location across Turkey (Türkiye) |
Conditions studied
- Periodontitis — all drugs for Periodontitis →
- Gingival Crevicular Fluid — all drugs for Gingival Crevicular Fluid →
- Interleukin 1-beta — all drugs for Interleukin 1-beta →
- Bactericidal Permeability Protein — all drugs for Bactericidal Permeability Protein →
Sponsor
Akdeniz University
Who can join
Eligibility, any sex, with Periodontitis or Gingival Crevicular Fluid. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Objective: The aim of this study is to determine the amounts of BPI (Bactericidal permeability protein) and interleukin-1beta (IL-1β) in gingival fluid samples obtained from individuals with periodontally healthy and periodontal disease, to compare these amounts between study groups, and to evaluate their relationship with clinical parameters. In cases where clinical parameters increase, IL-1β amounts also increase significantly. The amount of IL-1β in individuals with periodontal disease is significantly higher compared to healthy individuals. There is positive correlation between BPI and clinical parameters. The amount of BPI in individuals with periodontal disease is significantly higher than in healthy individuals. More studies are needed to better understand the importance and therapeutic effect of BPI in periodontitis
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06295666
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06295666 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Akdeniz University
- Last refreshed: 6 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06295666.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing