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NCT06287723

French Assessment of MRD by Liquid Biopsies in Colorectal With Liver Metastasis Patients (FRENCH.MRD.CRLM)

Not yet recruiting Last updated 1 March 2024
What this trial tests

trial testing Blood sample/Liquid biopsy in Colorectal Cancer in 30 participants. Not yet recruiting.

Timeline
1 March 2024
Primary endpoint
31 October 2025
31 October 2028

Quick facts

Lead sponsorUniversity Hospital, Montpellier
StatusNot yet recruiting
Study typeOBSERVATIONAL
Enrollment30
Start date1 March 2024
Primary completion31 October 2025
Estimated completion31 October 2028

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital, Montpellier

Who can join

18 and older, any sex, with Colorectal Cancer or Liver Metastases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Improving personalized cancer treatments and finding the best strategies to treat each patient relies on using new diagnostic technologies. Currently, for colorectal cancer, the methods used to decide who gets additional post-surgery treatment are suboptimal. Some patients get too much treatment, while others do not get enough. There is a new way to explore if there is any cancer left in a patient's body using circulating tumor DNA (ctDNA) detected in blood samples. This can help decide who needs more treatment after surgery. Even though many tests have been developed, it has yet to be determined which test performs best at relevant time points. The GUIDE.MRD consortium is a group of experts, including scientists, technology, and pharmaceutical companies. The consortium is working on creating a reliable standard for the ctDNA tests, validating their clinical utility, and collecting data to help decide on the best treatment for each patient. FRENCH.MRD.CRLM is the French study and part of the european GUIDE.MRD project.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Japan society of clinical oncology position paper on appropriate clinical use of molecular residual disease (MRD) testing.
    Kobayashi S, Nakamura Y, Hashimoto T, Bando H, et al · · 2025 · cited 6× · PMID 39920551 · DOI 10.1007/s10147-024-02683-0
  2. Liquid Biopsies in the Early Diagnosis, Prognosis, and Tailored Treatment of Colorectal Cancer.
    Liatsou E, Kollias I, Trapali M, Tsilimigras DI, et al · · 2025 · cited 4× · PMID 40149264 · DOI 10.3390/cancers17060927

Verify or expand the search:

Other recruiting trials for Colorectal Cancer

Currently open trials in the same condition.

Other University Hospital, Montpellier trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06287723.

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