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NCT06287489
Effects of Mediterranean Diet on Subjective Cognitive Decline
NA trial testing Mediterranean diet in Subjective Cognitive Decline in 57 participants. Completed in 2 December 2024.
2 December 2024
Quick facts
| Lead sponsor | Chih-Ping Chung |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 57 |
| Start date | 26 October 2023 |
| Primary completion | 2 December 2024 |
| Estimated completion | 2 December 2024 |
| Sites | 1 location across Taiwan |
Drugs / interventions tested
- Mediterranean diet
- Regular diet
Conditions studied
- Subjective Cognitive Decline — all drugs for Subjective Cognitive Decline →
Sponsor
Chih-Ping Chung
Who can join
60 and older, any sex, with Subjective Cognitive Decline. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Research Questions: 1. Due to the fact that most participants in past clinical trials on the Mediterranean diet were cognitively healthy individuals, and while the observed effects were significant, they were not particularly substantial, does the Mediterranean diet have similarly significant and more pronounced effects on both physical and cognitive functions in older adults with subjective cognitive decline (SCD)? 2. What is the mechanism behind the effects of the Mediterranean diet on physical or/and cognitive function? Is it through vascular protection or improvements in brain structure/brain network function? Research Objective: Conduct a cross-over randomized controlled trial to investigate the effects of a three-month Mediterranean diet on the physical and cognitive functions of older adults with subjective cognitive decline (SCD) in the community. Utilize brain MRI and circulatory biomarkers measurements to elucidate the underlying mechanisms.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06287489
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Mediterranean diet
Trials testing the same drug.
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- NCT07017127 — Remission of Type 2 Diabetes With Lifestyle Intervention · NA · recruiting
- NCT07055620 — Effects of Different Dietary Models on Eating Behavior and Obesity Management in Overweight and Obese Individuals · NA · completed
- NCT06774079 — Glucagon-like Peptide-1 Receptor Agonist (GLP-1 RA) and Diet in Inflammatory Bowel Disease (IBD) Patients · Phase 4 · recruiting
- NCT06765369 — How the Mediterranean Diet Affects You: Predicting Responses Based on Your Microbiome · NA · not yet recruiting
Other recruiting trials for Subjective Cognitive Decline
Currently open trials in the same condition.
- NCT07511270 — Prediction of Cognitive Test Performance Using AI-Based Analysis of Narrative Speech · NA · recruiting
- NCT07085663 — Exergame-assisted Simultaneous Motor-cognitive Training for Middle-aged Old Adults in China · NA · recruiting
- NCT06002477 — Attentional Mechanisms in SCD · EARLY_PHASE1 · recruiting
- NCT06358404 — Developing a Peer Support Intervention for Depression in SCD · NA · recruiting
- NCT06335836 — The Effects of Social Isolation and Social Interaction on the Risk of Dementia Progression and Brain Function in SCD (Su · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06287489 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Chih-Ping Chung
- Last refreshed: 9 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06287489.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing