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NCT06286280: ROCKSTAR
Removal Of CytoKines With cytoSorbenTs After Inflammatory Response Reaction During Cardiac Surgery
NA trial testing cytokine adsorber (CytoSorb®) in Inflammatory Response in 50 participants. Completed in 27 March 2025.
1 December 2024
Quick facts
| Lead sponsor | University of Giessen |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 50 |
| Start date | 1 May 2023 |
| Primary completion | 1 December 2024 |
| Estimated completion | 27 March 2025 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- cytokine adsorber (CytoSorb®)
Conditions studied
- Inflammatory Response — all drugs for Inflammatory Response →
Sponsor
University of Giessen
Who can join
18 and older, any sex, with Inflammatory Response. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Detailed knowledge about the association between systemic inflammation and endothelial progenitor cell (EPCs) activation during extracorporeal circulation (ECC) is lacking. This pilot study aims to clarify the relationship between CD34-positive EPCs and cytokine release during ECC using the cytokine adsorber to make a predictive statement regarding the clinical expression of inflammation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06286280
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University of Giessen trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06286280 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Giessen
- Last refreshed: 6 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06286280.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing