NCT06285032 (DLoop) is a NA clinical trial of Cognitive Behavior Therapy (CBT) in Loneliness, sponsored by University of Washington.

Who is sponsoring NCT06285032?

NCT06285032 is sponsored by University of Washington.

What drugs are being tested in NCT06285032?

Interventions in NCT06285032: Cognitive Behavior Therapy (CBT), Social Navigation Group, Controlled Group.

What condition does NCT06285032 study?

NCT06285032 studies Loneliness, Opioid Use.

Is NCT06285032 still recruiting?

NCT06285032 is currently completed. Last updated 12 January 2026.

Last reviewed 2026-01-12 · How we verify

NCT06285032: DLoop

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Decreasing Loneliness to Optimize Pain Care

Completed NA Last updated 12 January 2026

What this trial tests

NA trial testing Cognitive Behavior Therapy (CBT) in Loneliness in 102 participants. Completed in 18 December 2025.

Timeline

9 August 2024

Primary endpoint
18 December 2025

18 December 2025

Quick facts

Lead sponsor	University of Washington
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	102
Start date	9 August 2024
Primary completion	18 December 2025
Estimated completion	18 December 2025
Sites	1 location across United States

Drugs / interventions tested

Cognitive Behavior Therapy (CBT)
Social Navigation Group
Controlled Group

Conditions studied

Loneliness — all drugs for Loneliness →
Opioid Use — all drugs for Opioid Use →

Sponsor

University of Washington

Who can join

18 and older, any sex, with Loneliness or Opioid Use. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Loneliness, which is the perceived feeling of insufficient personal relationships, is related to higher risk for inappropriate opioid use and opioid use disorders in patients who are taking opioids long-term. The study seeks to pilot test the evidence-based loneliness interventions of psychological therapy and social navigation in patients on chronic opioids treated in primary care practices to determine if reducing loneliness can lower opioid misuse.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Comparing cognitive behavioral therapy and social prescribing in patients with loneliness on long-term opioid therapy to reduce opioid misuse: protocol for a randomized controlled trial.
Tong ST, Ma KPK, Pleho A, Keiser B, et al · · 2024 · PMID 39261953 · DOI 10.1186/s13722-024-00498-y

Verify or expand the search:

Other trials of Cognitive Behavior Therapy (CBT)

Trials testing the same drug.

NCT06164756 — Long Term Follow Up KET-PD · enrolling by invitation
NCT04328103 — Mechanisms of Emotion Regulation Underlying Successful CBT in Depression · completed
NCT03678766 — CHARGE: Controlling Hunger and ReGulating Eating · NA · completed

Other recruiting trials for Loneliness

Currently open trials in the same condition.

NCT07486050 — The Impact of Social Worker Referrals on Diabetes and Loneliness · NA · active not recruiting
NCT07443813 — An Innovative App-based Intervention to Promote Social Connectedness and Well-being in Older Adults · NA · active not recruiting
NCT07305701 — Cohort Study on Medical Students' Mental Health · recruiting
NCT07107906 — Evaluating and Implementing The CONNECT Program - a Group-Based Telehealth Intervention to Reduce Social Isolation, Lone · NA · recruiting
NCT06919094 — A Virtual Life Story Club Intervention to Improve Loneliness and Apathy in Community-Dwelling Older Adults · NA · recruiting

Other University of Washington trials

Trials by the same sponsor.

NCT07430852 — Inherited and Environmental Risks Acting on Body Weight · NA · not yet recruiting
NCT07466498 — Estrogen to Improve Quality of Life for Men With Newly Diagnosed or Recurrent Metastatic Hormone Sensitive Prostate Canc · Phase 2 · not yet recruiting
NCT06422299 — Developing and Testing an Online Intervention for Alcohol and Cannabis Misuse and Healthy Relationship Skills Among Youn · NA · not yet recruiting
NCT07322341 — SX-682 and Atezolizumab for the Treatment of Advanced or Metastatic, Recurrent Non-small Cell Lung Cancer · Phase 2 · not yet recruiting
NCT07332351 — Neoadjuvant Intravesical Nadofaragene Firadenovec With Gemcitabine, Cisplatin and Durvalumab for the Treatment of Muscle · Phase 2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06285032 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Washington
Last refreshed: 12 January 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06285032.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing