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NCT06284356

Pan Immune Inflammation Value for Perioperative Complications of Laparoscopic Sleeve Gastrectomy

Completed Last updated 1 March 2024
What this trial tests

trial testing Laparoscopic Sleeve Gastrectomy in Morbid Obesity in 159 participants. Completed in 1 May 2023.

Timeline
1 May 2022
Primary endpoint
1 May 2023
1 May 2023

Quick facts

Lead sponsorKahramanmaras Sutcu Imam University
StatusCompleted
Study typeOBSERVATIONAL
Enrollment159
Start date1 May 2022
Primary completion1 May 2023
Estimated completion1 May 2023
Sites1 location across Turkey (Türkiye)

Drugs / interventions tested

Conditions studied

Sponsor

Kahramanmaras Sutcu Imam University

Who can join

18 and older, any sex, with Morbid Obesity or Laparoscopic Sleeve Gastrectomy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Morbid obesity emerges as a problem that causes serious complications and increased mortality rates. The most effective treatment for morbid obesity today is surgical treatment. The most preferred type of surgery in morbid obesity surgery in Turkey and around the world is Laparoscopic Sleeve Gastrectomy (LSG). While postoperative complications are divided into early and late complications, complications that develop during surgery and in the postoperative period before discharge are defined as perioperative complications. Early surgical complications after LSG include complications such as staple line bleeding, leaks, pulmonary thromboembolism, and torsion of the remnant stomach. It is important to detect these complications, which can be controlled with early intervention in the perioperative period. Monitoring blood parameters and monitoring inflammation are methods that are easily accessible and provide rapid evaluation. Platelet lymphocyte ratio (PLR) and neutrophil-lymphocyte ratio (NLR), which are used in the evaluation and detection of postoperative complications, have shed light on studies in this direction. Pan immune inflammation value (PIV) is calculated from blood parameters and has been used to evaluate prognosis and chemotherapy results in colorectal cancer. In this study, the diagnostic importance of changes in NLR, PLR, and PIV values in the preoperative and postoperative periods will be investigated in detecting complications that develop in the perioperative period before discharge in patients who underwent LSG.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Pan-Immune Inflammation Value in Detecting Perioperative Complications in Patients Undergoing Laparoscopic Sleeve Gastrectomy: A Prospective Cohort Study.
    Kutluer N, Aksu A, Bozan MB, Ayyildiz H, et al · · 2026 · PMID 41894132 · DOI 10.1007/s11695-026-08626-0

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