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NCT06282757
Physiotherapists' Placebo or Nocebo Communication Regarding VR in CMP
NA trial testing Video placebo communication in Communication in 115 participants. Completed in 30 June 2024.
30 June 2024
Quick facts
| Lead sponsor | HAN University of Applied Sciences |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | other |
| Enrollment | 115 |
| Start date | 1 April 2024 |
| Primary completion | 30 June 2024 |
| Estimated completion | 30 June 2024 |
| Sites | 1 location across Netherlands |
Drugs / interventions tested
- Video placebo communication
- Video nocebo communication
Conditions studied
- Communication — all drugs for Communication →
- Chronic Pain — all drugs for Chronic Pain →
Sponsor
HAN University of Applied Sciences
Who can join
18 and older, any sex, with Communication or Chronic Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Rationale: Chronic musculoskeletal pain (CMP) is a common and disabling condition. Physiotherapy is the most frequently administered non-pharmacological treatment option for patients with CMP and recently virtual reality (VR) was introduced in physiotherapy care as a novel treatment modality. Proper communication about physiotherapy treatment (modalities) is important to improve treatment outcomes, by applying placebo effects enhancing communication and avoiding nocebo effects enhancing communication. However, yet is still unknown to what extent this applies to communication of physiotherapists about VR in patients with CMP. Objective: To determine the effect of physiotherapists' placebo or nocebo therapeutic communication about VR, on treatment credibility and expectation in patients with CMP Study design: Web-based randomized controlled trial. Study population: 100 participants Intervention: The placebo intervention group will be shown an educational video about VR, containing placebo effects enhancing verbal language. The nocebo intervention group will be shown an educational video about VR, containing nocebo effects enhancing verbal language. Primary study parameters: The primary study parameters are treatment credibility and treatment expectation. Treatment credibility and treatment expectations will be measured using the Dutch credibility and expectancy questionnaire (CEQ).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The effect of physiotherapists' explanation of therapeutic virtual reality on treatment expectations in healthy people and people with chronic musculoskeletal pain: Two online RCTs.
Slatman S, van Lankveld W, Staal JB, van Goor H, et al · · 2026 · PMID 41362581 · DOI 10.1016/j.pecinn.2025.100443
Verify or expand the search:
- PubMed search for NCT06282757
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Video nocebo communication
Trials testing the same drug.
- NCT06307912 — Physiotherapists' Placebo or Nocebo Communication Regarding VR · NA · completed
Other recruiting trials for Communication
Currently open trials in the same condition.
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- NCT07137377 — Assessing the Impact of Therapeutic Communication on Patients' Anxiety During Elective Cesarean Sections · NA · recruiting
Other HAN University of Applied Sciences trials
Trials by the same sponsor.
- NCT07390227 — Virtual Reality Intervention in Patients With Persistent Shoulder Pain · NA · not yet recruiting
- NCT06626360 — Screening for Malnutrition in Obese Patients · recruiting
- NCT06307912 — Physiotherapists' Placebo or Nocebo Communication Regarding VR · NA · completed
- NCT05593302 — The Effectiveness of Trauma Focused Art Therapy · NA · completed
- NCT03032237 — Increase Protein Intake of Older Meal Service Clients With Readymade Protein-rich Meals and Foods · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06282757 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by HAN University of Applied Sciences
- Last refreshed: 16 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06282757.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing