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NCT06281340
Changes in Intra-articular Parameters by Doppler Ultrasound in Patients With Hemophilic Ankle Arthropathy
NA trial testing Manual therapy in Hemophilia in 20 participants. Completed in 21 April 2024.
10 April 2024
Quick facts
| Lead sponsor | Investigación en Hemofilia y Fisioterapia |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | diagnostic |
| Enrollment | 20 |
| Start date | 28 February 2024 |
| Primary completion | 10 April 2024 |
| Estimated completion | 21 April 2024 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Manual therapy
- Placebo manual therapy
Conditions studied
- Hemophilia — all drugs for Hemophilia →
Sponsor
Investigación en Hemofilia y Fisioterapia
Who can join
Adults 30 to 55, male only, with Hemophilia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Introduction: Hemophilic ankle arthropathy is manifested by functional degenerative alterations, intra-articular alterations, and chronic pain. Manual therapy techniques are used in the treatment of hemophilic ankle arthropathy for the improvement of pain and mobility. Design. Double-blind randomized pilot trial. Aimed: To evaluate the ultrasound changes by means of Doppler imaging after manual therapy intervention. Patients: A total of 20 adult patients with hemophilic ankle arthropathy will be recruited. Intervention: Each manual therapy session will last approximately 50 minutes, with 1 session per week for a period of 3 weeks. The treatment program includes 10 techniques that will be administered bilaterally. Measuring instruments: Patients will be evaluated qualitatively with ultrasound (HEAD-US scale) and assessment with Doppler ultrasound. The clinical variables will be joint damage (Hemophilia Joint Health Score) and pain intensity (Visual Analogue Scale). Expected results: Check the safety of manual therapy in patients with hemophilia regarding subclinical bleeding. Assess changes related to joint inflammatory state with imaging techniques. Observe changes in pain intensity and joint damage.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06281340
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Hemophilia
Currently open trials in the same condition.
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Other Investigación en Hemofilia y Fisioterapia trials
Trials by the same sponsor.
- NCT07516730 — Central Pain Mechanisms and Clinical and Psychological Factors Associated With Pain Interference in Daily Life in Adults · not yet recruiting
- NCT07483541 — Identification of Modifiable Sleep-related Factors in Patients With Systemic Lupus Erythematosus. · not yet recruiting
- NCT07420387 — Effectiveness of an Educational Program for Pain Management in Patients With Hemophilic Arthropathy · NA · not yet recruiting
- NCT07420348 — Incidence of Ultrasonographically Detected Articular Damage in Initially Healthy Joints of Patients With Hemophilia A Re · not yet recruiting
- NCT07123220 — Prognostic Factors for Fatigue in Patients With Systemic Lupus Erythematosus · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06281340 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Investigación en Hemofilia y Fisioterapia
- Last refreshed: 24 May 2024
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