Who is sponsoring NCT06281145?

NCT06281145 is sponsored by Comenius University.

What drugs are being tested in NCT06281145?

Interventions in NCT06281145: Heart-rate variability biofeedback intervention.

What condition does NCT06281145 study?

NCT06281145 studies Breast Cancer, Colon Cancer.

Is NCT06281145 still recruiting?

NCT06281145 is currently recruiting now. Last updated 28 February 2024.

Last reviewed 2024-02-28 · How we verify

NCT06281145: SRI-BrCa_CRC

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Stress-Reducing Intervention in Patients With Colorectal and Breast Cancer

Recruiting now NA Last updated 28 February 2024

What this trial tests

NA trial testing Heart-rate variability biofeedback intervention in Breast Cancer in 100 participants. Currently enrolling.

Timeline

15 March 2024

Primary endpoint
15 March 2027

15 March 2029

Quick facts

Lead sponsor	Comenius University
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	supportive care
Enrollment	100
Start date	15 March 2024
Primary completion	15 March 2027
Estimated completion	15 March 2029
Sites	1 location across Slovakia

Drugs / interventions tested

Heart-rate variability biofeedback intervention

Conditions studied

Breast Cancer — all drugs for Breast Cancer →
Colon Cancer — all drugs for Colon Cancer →

Sponsor

Comenius University

Who can join

18 and older, any sex, with Breast Cancer or Colon Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this interventional study is to test the heart-rate variability biofeedback intervention (HRV BI) in 2 cohorts of patients. Cohort A will evaluate the effect of the addition of HRV BI in patients with breast cancer treated in the neoadjuvant setting (vs. standard of care alone, SOC) followed by local therapy (surgery +/-radiotherapy). Cohort B will evaluate the effect of the addition of HRV BI in patients with colon cancer after surgery in the adjuvant setting (vs. standard of care alone, SOC).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Cancer Neoaxonogenesis: Mechanisms and Factors Involved in the Recruitment of Peripheral Nerves by Cancer Tissue.
Blasko F, Horvathova L, Hunakova L, Krivosikova L, et al · · 2026 · PMID 42123376 · DOI 10.3390/ijms27093792
EACR 2025 Congress: Innovative Cancer Science, 16-19 June 2025.
· 2025 · PMID 40498965 · DOI 10.1002/1878-0261.70070

Verify or expand the search:

Other recruiting trials for Breast Cancer

Currently open trials in the same condition.

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NCT07405801 — A Phase II Study Evaluating the Efficacy and Safety of Inavolisib Plus Ribociclib Plus Fulvestrant Versus Placebo Plus R · Phase 2 · recruiting
NCT07285993 — Detection and Outcomes in Metastatic Invasive Lobular Breast Cancer Through Novel F-18 FAP PET · Phase 2 · recruiting
NCT07510698 — Same-Day Awake Mastectomy With Immediate Breast Reconstruction for Patients With Breast Cancer · NA · recruiting
NCT06768931 — Biolosion Combined Standard Neoadjuvant Therapy to Treat Triple-negative Breast Cancer · Phase 2 · recruiting

Other Comenius University trials

Trials by the same sponsor.

NCT07522905 — Virtual Buddy Movement Therapy for Psychomotor and Social Development in Pediatric Oncology Patients in Remission · NA · not yet recruiting
NCT07446556 — Exercise Program in Women With Pudendal Neuralgia · NA · enrolling by invitation
NCT07465809 — Mental Health Resources and Employability in Healthcare · NA · completed
NCT07442838 — Clinical Outcomes and Complications in Two-stage Breast Reconstruction Using Microtextured and Nanotextured Expanders · active not recruiting
NCT06842615 — Prospective Evaluation of Diagnostic Performance of PanTum Detect Test in Adult Patients With Suspected or Confirmed Mac · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06281145 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Comenius University
Last refreshed: 28 February 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06281145.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing