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NCT06278428
Genotype, Phenotype, and Disease Progression of Developmental Epileptic Encephalopathy With Onset Before 2 Years of Age
trial in Epilepsy; Seizure in 50 participants. Currently enrolling.
1 November 2028
Quick facts
| Lead sponsor | Number 2 Children's Hospital, Ho Chi Minh City |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 27 February 2024 |
| Primary completion | 1 November 2028 |
| Estimated completion | 1 November 2028 |
| Sites | 2 locations across Vietnam |
Conditions studied
- Epilepsy; Seizure — all drugs for Epilepsy; Seizure →
- Child Development — all drugs for Child Development →
- Gene Abnormality — all drugs for Gene Abnormality →
- Early Onset Disorder — all drugs for Early Onset Disorder →
Sponsor
Number 2 Children's Hospital, Ho Chi Minh City
Who can join
Under 23 Months, any sex, with Epilepsy; Seizure or Child Development. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
According to estimates by the World Health Organization in 2019, more than 50 million people around the world have epilepsy. Nearly 80% of patients with epilepsy live in developing countries. Among them, children under 2 years old are the group with the highest incidence of epilepsy, and at the same time, the most dangerous epilepsy groups are also likely to start at these ages. World medical literature on epileptic encephalopathy and early-onset development before 2 years of age records that 71% of children have severe intellectual disability and 60% of children show signs of autism spectrum disorder, of which Children with epileptic and developmental encephalopathy due to genetic causes are at higher risk of developing neurodevelopmental disorders than children with epileptic and developmental encephalopathy due to other causes. However, in Vietnam, there is no research on this topic. The question is what are the phenotypes, genotypes, and progression after 2 years of follow-up of Vietnamese children with epileptic and developmental encephalopathy with onset before 2 years of age?
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06278428
- Europe PMC full search
- ASCO Meeting Library
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Related trials
Other recruiting trials for Epilepsy; Seizure
Currently open trials in the same condition.
- NCT04569708 — Sleep Spindles and Memory in Rolandic Epilepsy · NA · recruiting
- NCT06617845 — Optimizing Brain Stimulation Parameters · NA · recruiting
Other Number 2 Children's Hospital, Ho Chi Minh City trials
Trials by the same sponsor.
- NCT05722990 — Genetic Investigations in Children With Developmental and Epileptic Encephalopathies in Ho Chi Minh City, Vietnam · unknown
- NCT05697887 — Feasibility, Tolerability and Efficacy of the Ketogenic Diet in Children With Drug-resistant Epilepsy in South Vietnam · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06278428 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Number 2 Children's Hospital, Ho Chi Minh City
- Last refreshed: 9 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06278428.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing