Last reviewed · How we verify
NCT06276023: SOCIAL
Supporting Our Caregivers In ADRD Learning (SOCIAL)
NA trial testing Mindful and Self-Compassionate Care Program (MASC) in Alzheimer's Disease and Related Dementias in 82 participants. Completed in 28 May 2025.
28 May 2025
Quick facts
| Lead sponsor | Massachusetts General Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | single group |
| Masking | single |
| Primary purpose | supportive care |
| Enrollment | 82 |
| Start date | 22 March 2024 |
| Primary completion | 28 May 2025 |
| Estimated completion | 28 May 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Mindful and Self-Compassionate Care Program (MASC)
- Health Education Program (HEP)
Conditions studied
- Alzheimer's Disease and Related Dementias — all drugs for Alzheimer's Disease and Related Dementias →
- Quality of Life — all drugs for Quality of Life →
- Caregiver Stress — all drugs for Caregiver Stress →
Sponsor
Massachusetts General Hospital
Who can join
18 and older, any sex, with Alzheimer's Disease and Related Dementias or Quality of Life. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Building on limitations of prior research, the investigators developed the Mindful and Self-Compassionate Care Program (MASC) to help caregivers of persons with Alzheimer Disease and Related Dementias (ADRD) manage stress associated with the general caregiver experience including stress stemming from managing challenging patient behaviors. MASC teaches: (1) mindfulness skills; (2) compassion and self-compassion skills; and (3) behavioral management skills. MASC also provides psychoeducation and group-based training and skill practice to facilitate skill uptake and integration within the caregiver experience and tasks. The main aim is to: Demonstrate feasibility, acceptability, credibility, fidelity, preliminary efficacy and evidence for proposed mechanism of MASC through a pilot randomized controlled trial. Relevant stakeholders (caregivers of persons with ADRD) will participate in the intervention.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Intervention for the Management of Neuropsychiatric Symptoms to Reduce Caregiver Stress: Protocol for the Mindful and Self-Compassion Care Intervention for Caregivers of Persons Living With Dementia.
Travis A, O'Donnell A, Giraldo-Santiago N, Stone SM, et al · · 2024 · cited 3× · PMID 39392675 · DOI 10.2196/58356
Verify or expand the search:
- PubMed search for NCT06276023
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Alzheimer's Disease and Related Dementias
Currently open trials in the same condition.
- NCT03848312 — Preventing Alzheimer's With Cognitive Training · Phase 3 · recruiting
Other Massachusetts General Hospital trials
Trials by the same sponsor.
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- NCT06686901 — A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior · NA · not yet recruiting
- NCT05854212 — Behavioral Economics to Implement Nutrition Ranking in Food Pantries · NA · not yet recruiting
- NCT07323446 — The MIND Study: The MGH/MIT Investigation of NAC on Dysregulation · EARLY_PHASE1 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06276023 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Massachusetts General Hospital
- Last refreshed: 13 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06276023.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing