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NCT06275438
Comparison of Oxytocin Receptor Immunoreactivity in Placentas Obtained From Women Having Cesarean and Natural Birth
NA trial testing The delivery being performed via cesarean section surgery rather than natural childbirth in Healthy Mothers Who Have Had Both Vaginal and Cesarean Deliveries in 32 participants. Completed in 1 December 2019.
1 July 2019
Quick facts
| Lead sponsor | Kafkas University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | health services research |
| Enrollment | 32 |
| Start date | 25 August 2018 |
| Primary completion | 1 July 2019 |
| Estimated completion | 1 December 2019 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- The delivery being performed via cesarean section surgery rather than natural childbirth
Conditions studied
- Healthy Mothers Who Have Had Both Vaginal and Cesarean Deliveries — all drugs for Healthy Mothers Who Have Had Both Vaginal and Cesarean Deliveries →
Sponsor
Kafkas University
Who can join
Adults 18 to 35, female only, with Healthy Mothers Who Have Had Both Vaginal and Cesarean Deliveries. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Our study examines the effects of oxytocin hormone receptors. mechanisms of placental tissue cells and therefore intrauterine development. It was conducted to investigate the effects on newborn babies apgar score, fontanel openings, birth weights, etc. By collecting data, normal and They were compared between cesarean births by statistical analysis. normal in this regard Based on the hypothesis that there is a difference between labor and cesarean delivery, this study has been made.OXTR primary antibody was used for immunohistochemical examination. There was no significant difference between the groups in terms of histological examination. In the study, it was found that OXTR immunoreactivity was strong in decidual cells and stromal cells in villi. A stronger OXTR immunoreactivity was detected in villous stroma of placenta of the natural birth group compared to the cesarean birth group. Reaction was not observed in syncytotrophoblast cells and syncytial nodes in both groups, but strong immunoreaction was observed fetal endothelial cells and fetal capillaries in both groups.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06275438 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kafkas University
- Last refreshed: 23 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06275438.
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