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NCT06275048
The Influence of Oral Contraceptives During Disuse
NA trial testing Wrist/hand immobilization in Oral Contraceptives in 41 participants. Completed in 25 March 2025.
25 March 2025
Quick facts
| Lead sponsor | University of Central Florida |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 41 |
| Start date | 26 January 2024 |
| Primary completion | 25 March 2025 |
| Estimated completion | 25 March 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Wrist/hand immobilization
Conditions studied
- Oral Contraceptives — all drugs for Oral Contraceptives →
- Rehabilitation — all drugs for Rehabilitation →
- Menstrual Cycle — all drugs for Menstrual Cycle →
- Physical Therapy — all drugs for Physical Therapy →
Sponsor
University of Central Florida
Who can join
Adults 18 to 35, any sex, with Oral Contraceptives or Rehabilitation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Studies across various sports and physical activities have consistently shown that females incur more injuries compared to their male counterparts, but the underlying reasons for this disparity remain poorly understood. While differences in hormone levels between males and females have been speculated to play a role, very little rigorous research has been conducted to directly examine potential connections between sex hormones and injury risk. Specifically, females have been shown to be at greater risk for hand and wrist injuries. The higher injury incidence begins at puberty and persists across the lifespan, suggesting a link to hormonal factors. However, significant gaps remain in understanding the relationships between the menstrual cycle, exogenous hormones from birth control, and risk factors for sports-related injury in females. The purpose of this study is to examine changes in muscle strength and neuromuscular activation among females using monophasic oral contraceptives, females not using oral contraceptives, and males during one week of wrist/hand immobilization.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06275048
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other recruiting trials for Oral Contraceptives
Currently open trials in the same condition.
- NCT07258576 — Menstrual Cycle vs. Oral Contraceptives: Effects on Muscle Protein Metabolism After Resistance Exercise · NA · recruiting
Other University of Central Florida trials
Trials by the same sponsor.
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- NCT06999057 — Quadriceps Motor Unit Adaptation to Simulated Knee Injury · NA · not yet recruiting
- NCT06979713 — Yoga, Education, and Nidra (YEN) for Chronic Low Back Pain: A Pilot Study on Pain Modulation, Well-Being, and Sleep · NA · not yet recruiting
- NCT06512168 — Measuring Aided Language Development · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06275048 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Central Florida
- Last refreshed: 22 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06275048.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing