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NCT06267209
Conditioned Pain Modulation in Patients With Hemophilia
trial testing Observational group in Hemophilia in 51 participants. Currently enrolling.
3 June 2024
Quick facts
| Lead sponsor | Investigación en Hemofilia y Fisioterapia |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 51 |
| Start date | 1 May 2024 |
| Primary completion | 3 June 2024 |
| Estimated completion | 20 June 2024 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Observational group
Conditions studied
- Hemophilia — all drugs for Hemophilia →
Sponsor
Investigación en Hemofilia y Fisioterapia
Who can join
Adults 20 to 65, male only, with Hemophilia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Introduction: Hemophilic arthropathy is characterized by functional alterations, disabling physical sequelae, and chronic pain. Conditioned pain modulation describes the net effect of endogenous pathways that enhance or diminish the effects of afferent noxious stimuli. Objectives: To describe conditioned pain modulation in patients with hemophilia and identify the best predictive model of conditioned pain modulation in these patients Methods: Cross-sectional cohort study. 51 patients with hemophilic arthropathy will be recruited in 3 regions of Spain. The main study variable will be the conditional pain modulation (Conditioned Pain Modulation Index, using an ischemic technique of the arm using the pain pressure threshold as a test stimulus), with age being the dependent variable. The secondary variables, estimated as modifying or confounding variables, will be kinesiophobia (Tampa Scale for Kinesiophobia), catastrophizing (Pain Catstrophizing Scale), trait and state anxiety (State-Trait Anxiety Inventory) and the main clinical, anthropometric, and sociodemographic. Expected results: Identify the degree of modulation conditioned by pain in patients with hemophilic arthropathy. Identify the best predictive model for conditioned pain modulation in these patients based on the study variables
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Conditioned Pain Modulation in Patients with Hemophilic Arthropathy: A Cross-Sectional Cohort Study.
Bermúdez-Egidos M, Pérez-Llanes R, Ucero-Lozano R, Cuesta-Barriuso R. · · 2025 · PMID 40095850 · DOI 10.3390/jcm14051728
Verify or expand the search:
- PubMed search for NCT06267209
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Other Investigación en Hemofilia y Fisioterapia trials
Trials by the same sponsor.
- NCT07516730 — Central Pain Mechanisms and Clinical and Psychological Factors Associated With Pain Interference in Daily Life in Adults · not yet recruiting
- NCT07483541 — Identification of Modifiable Sleep-related Factors in Patients With Systemic Lupus Erythematosus. · not yet recruiting
- NCT07420387 — Effectiveness of an Educational Program for Pain Management in Patients With Hemophilic Arthropathy · NA · not yet recruiting
- NCT07420348 — Incidence of Ultrasonographically Detected Articular Damage in Initially Healthy Joints of Patients With Hemophilia A Re · not yet recruiting
- NCT07123220 — Prognostic Factors for Fatigue in Patients With Systemic Lupus Erythematosus · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06267209 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Investigación en Hemofilia y Fisioterapia
- Last refreshed: 24 May 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06267209.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing