NCT06266598 is a Phase 4 clinical trial of Metformin in Childhood Obesity, sponsored by HÜMEYRA ACIKAN.

Who is sponsoring NCT06266598?

NCT06266598 is sponsored by HÜMEYRA ACIKAN.

What drugs are being tested in NCT06266598?

Interventions in NCT06266598: Metformin.

What condition does NCT06266598 study?

NCT06266598 studies Childhood Obesity, Insulin Resistance.

Is NCT06266598 still recruiting?

NCT06266598 is currently completed. Last updated 20 February 2024.

Last reviewed 2024-02-20 · How we verify

NCT06266598

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effectiveness of Antidiabetic Treatment Applied in Childhood Obesity

Completed Phase 4 Last updated 20 February 2024

What this trial tests

Phase 4 trial testing Metformin in Childhood Obesity in 52 participants. Completed in 27 October 2021.

Timeline

17 November 2019

Primary endpoint
20 August 2021

27 October 2021

Quick facts

Lead sponsor	HÜMEYRA ACIKAN
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	52
Start date	17 November 2019
Primary completion	20 August 2021
Estimated completion	27 October 2021
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

Metformin (metformin) — full drug profile →

Conditions studied

Childhood Obesity — all drugs for Childhood Obesity →
Insulin Resistance — all drugs for Insulin Resistance →

Sponsor

HÜMEYRA ACIKAN

Who can join

Adults 9 to 18, any sex, with Childhood Obesity or Insulin Resistance. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In our study, there are 33 healthy children with normal weight (control group) and 52 obese children who will be treated with metformin. To observe the efficacy of the 3-month treatment before and after metformin treatment, Zn, Zinc α-2 Glycoprotein (ZAG), Peroxisome proliferation activating receptor γ (PPARγ), Leptin (LEP) and Adiponectin (ADIPO) levels were compared, as well as anthropometric measurements and routine biochemistry tests.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Nuclear receptors in health and disease: signaling pathways, biological functions and pharmaceutical interventions.
Jin P, Duan X, Huang Z, Dong Y, et al · · 2025 · cited 21× · PMID 40717128 · DOI 10.1038/s41392-025-02270-3
The role of short-term metformin in regulating zinc and adipose tissue-derived biomarkers in children with obesity and insulin resistance.
Acikan H, Isik A, Sarikaya E, Muhtaroglu S, et al · · 2026 · PMID 41501800 · DOI 10.1186/s12902-025-02159-w

Verify or expand the search:

Other trials of Metformin

Trials testing the same drug.

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NCT07520110 — Metformin to Attenuate Progressive Respiratory Decline in Idiopathic Pulmonary Fibrosis · Phase 3 · not yet recruiting
NCT07007221 — Clinical Trials to Evaluate Metformin to Treat Depression in People Living With HIV · Phase 2 · not yet recruiting
NCT07585396 — Inositol in Letrozol Resistant PCOS Women · Phase 2, PHASE3 · not yet recruiting
NCT07226453 — Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma · Phase 2 · not yet recruiting

Other recruiting trials for Childhood Obesity

Currently open trials in the same condition.

NCT06836284 — The Evira Study: Additional Support During Obesity Treatment · NA · recruiting
NCT07467694 — Postnatal Exercise to Activate Baby's Brown Fat · NA · recruiting
NCT07184281 — Effectiveness of School-Based Time-Restricted Eating for the Prevention and Control of Obesity in Children · NA · recruiting
NCT07103343 — MOVI-OLE! [Open Learning Environments] · NA · active not recruiting
NCT06918821 — Reducing Obesity Through Play Among Toddlers: Tiny Steps to Health (TSHS) Study · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06266598 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by HÜMEYRA ACIKAN
Last refreshed: 20 February 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06266598.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing