NCT06260501

Wetting Solution-ideal Body Weight Ratio in Liposuction Procedures

Completed Last updated 15 February 2024

What this trial tests

trial testing super-wet technique in Liposuction in 192 participants. Completed in 30 October 2023.

Timeline

1 September 2021

Primary endpoint
30 September 2023

30 October 2023

Quick facts

Lead sponsor	Acibadem University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	192
Start date	1 September 2021
Primary completion	30 September 2023
Estimated completion	30 October 2023
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• super-wet technique

Conditions studied

• Liposuction — all drugs for Liposuction →
• Obesity — all drugs for Obesity →
• Postoperative Complications — all drugs for Postoperative Complications →

Sponsor

Acibadem University

Who can join

18 and older, any sex, with Liposuction or Obesity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Although the use of wetting solutions during high-volume liposuction is a standard approach, it is unclear how to optimize wetting solutions and components and their effect on postoperative complications.. Since the super-wet technique (aspiration of 1 cc per 1 cc of infiltrate) was introduced in 1986, it has become one of the most frequently applied techniques worldwide . Adrenaline and lidocaine are often added to WS due to their hemostatic and analgesic effects One of the major advantages of super-wet technique is that blood loss is quite low. However, potential cardiovascular side effects of WS and the amounts of epinephrine and lidocaine they contain, such as volume overload, local anesthetic toxicity, hypertension, arrhythmia, and tachycardia, are still a scoop of investigation. In this study, we examined the WS and the medications it contains from a different perspective to understand the possible cause of these adverse outcomes. Despite the most suitable candidates for liposuction are patients with a BMI\<30 kg/m2 and low comorbidity and age, the patient group undergoing liposuction is often obese, and overweight individuals require that obesity-related pathophysiological changes be taken into consideration. Therefore, we analyzed the patients by dividing them into two groups according to the amount of WS applied according to their IBW (WS/IBW≤90ml/kg: group I and WS/IBW\>90ml/kg: group I). In this study we aimed to evaluate the effect of wetting solutions and components calculated according to ideal body weight (IBW) on postoperative complications

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Relationship between Postoperative Complications and Ratio of Amount of Wetting Solution to Ideal Body Weight in Liposuction Procedures.
   Aktas Yildirim S, Dogan L, Sarikaya ZT, Gucyetmez B, et al · · 2024 · PMID 38793076 · DOI 10.3390/jpm14050494