Last reviewed · How we verify
NCT06258434: COLO-LIMULOID
Liquid Biopsy Based Multiomics Study for Colorectal Cancer Early Screening
trial testing multiomics Colorectal Cancer (CRC) screening test (CRC-Appareo) in Colorectal Cancer in 1,000 participants. Status unknown.
10 August 2024
Quick facts
| Lead sponsor | Sir Run Run Shaw Hospital |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 1,000 |
| Start date | 10 February 2024 |
| Primary completion | 10 August 2024 |
| Estimated completion | 10 September 2024 |
| Sites | 1 location across China |
Drugs / interventions tested
- multiomics Colorectal Cancer (CRC) screening test (CRC-Appareo)
Conditions studied
- Colorectal Cancer — all drugs for Colorectal Cancer →
- Adenomatous Polyps — all drugs for Adenomatous Polyps →
- Adenoma — all drugs for Adenoma →
- Advanced Adenoma — all drugs for Advanced Adenoma →
Sponsor
Sir Run Run Shaw Hospital
Who can join
Adults 40 to 74, any sex, with Colorectal Cancer or Adenomatous Polyps. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The primary objective is to determine the diagnostic sensitivity and specificity of the newly developed liquid biopsy based multiomics Colorectal Cancer (CRC) screening test (CRC-Appareo) for detecting advanced neoplasia (including colorectal cancer and advanced adenomas) in high risk patients and patients with confirmed CRC, using colonoscopy as the reference method. The secondary objective is to compare the screening performance of the multiomics Colorectal Cancer (CRC) screening test with commercially available FIT (Fecal Immunochemical Test) assay in detecting advanced neoplasia.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Liquid biopsy biomarkers for early detection of gastrointestinal cancers: Current landscape and emerging technologies.
Anees M, Sherry C, Park HY, Grayhack EE, et al · · 2026 · PMID 41866828 · DOI 10.1002/ctm2.70594
Verify or expand the search:
- PubMed search for NCT06258434
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Sir Run Run Shaw Hospital trials
Trials by the same sponsor.
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- NCT07514533 — The Efficacy and Safety of Pucotenlimab (PD-1) Combined With Becotatugvedotin (EGFR-ADC) in Advanced Cholangiocarcinoma · Phase 2 · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06258434 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sir Run Run Shaw Hospital
- Last refreshed: 14 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06258434.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing