NCT06252636

Evaluation of the Efficacy and Safety of A2 Milk on Digestion

Active, enrolled NA Last updated 29 November 2024

What this trial tests

NA trial testing A2 Milk in Digestive Discomfort in 40 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

7 April 2023

Primary endpoint
20 November 2023

30 April 2025

Quick facts

Lead sponsor	Seoul National University Bundang Hospital
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	other
Enrollment	40
Start date	7 April 2023
Primary completion	20 November 2023
Estimated completion	30 April 2025
Sites	1 location across South Korea

Drugs / interventions tested

• A2 Milk
• A1/A2 Milk

Conditions studied

• Digestive Discomfort — all drugs for Digestive Discomfort →

Sponsor

Seoul National University Bundang Hospital

Who can join

Adults 20 to 70, any sex, with Digestive Discomfort. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to evaluate the efficacy and safety of A2 milk versus a control (A1/A2 milk) in individuals with digestive discomfort following milk consumption.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

1. The Effect of A2 Milk on Gastrointestinal Symptoms in Comparison to A1/A2 Milk: A Single-center, Randomized, Double-blind, Cross-over Study.
   Choi Y, Kim N, Song CH, Kim S, et al · · 2024 · cited 7× · PMID 38957588 · DOI 10.15430/jcp.24.007
2. Beneficial effect of consuming milk containing only A2 beta-casein on gut microbiota: A single-center, randomized, double-blind, cross-over study.
   Song CH, Kim N, Choi Y, Kim S, et al · · 2025 · cited 1× · PMID 40338897 · DOI 10.1371/journal.pone.0323016
3. UEG Week 2024 Moderated Posters
   · 2024