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NCT06251648

Acute Lymphoblastic Leukaemia Related to Lenalidomide (LenALL)

Status unknown Last updated 9 February 2024
What this trial tests

trial testing Lenalidomide in Cancer in 300 participants. Status unknown.

Timeline
1 February 2024
Primary endpoint
15 February 2024
31 March 2024

Quick facts

Lead sponsorUniversity Hospital, Caen
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment300
Start date1 February 2024
Primary completion15 February 2024
Estimated completion31 March 2024
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital, Caen

Who can join

18 and older, any sex, with Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Although lenalidomide (LEN) have proved effective in treating many cancers, few patients receiving LEN may experience rare but life-threatening adverse events such as Acute Lymphoblastic Leukaemia (ALL). Today, data about ALL are scarce. The objective was to investigate reports of ALL adverse events related to LEN in patients with cancer using the World Health Organization (WHO) pharmacovigilance database.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Acute lymphoblastic leukemia in patients treated with lenalidomide for multiple myeloma: a safety meta-analysis of randomized controlled trials combined with a retrospective study of the WHO's pharmacovigilance database.
    Morice PM, Khalife-Hachem S, Sassier M, Lelong-Boulouard V, et al · · 2024 · cited 3× · PMID 39402057 · DOI 10.1038/s41408-024-01154-z
  2. EHA2024 Hybrid Congress
    · 2024

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Other trials of Lenalidomide

Trials testing the same drug.

Other recruiting trials for Cancer

Currently open trials in the same condition.

Other University Hospital, Caen trials

Trials by the same sponsor.

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Data sources for this page

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