Last reviewed · How we verify
NCT06249776: GRASSROOT
Gravity Stent-Retriever System For Reperfusion Of Large Vessel Occlusion Stroke Trial
NA trial testing Supernova revascularization device in Ischemic Stroke in 54 participants. Completed in 14 April 2026.
14 April 2026
Quick facts
| Lead sponsor | Gravity Medical Technology, INC |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 54 |
| Start date | 9 February 2024 |
| Primary completion | 14 April 2026 |
| Estimated completion | 14 April 2026 |
| Sites | 11 locations across Pakistan, Iran, India |
Drugs / interventions tested
- Supernova revascularization device
Conditions studied
- Ischemic Stroke — all drugs for Ischemic Stroke →
- Stroke — all drugs for Stroke →
- Cerebrovascular Disorders — all drugs for Cerebrovascular Disorders →
- Brain Diseases — all drugs for Brain Diseases →
Sponsor
Gravity Medical Technology, INC
Who can join
Adults 18 to 85, any sex, with Ischemic Stroke or Stroke. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study aims to evaluate the safety and efficacy of the Supernova stent retriever device, developed by Gravity Medical Technology, for treating acute ischemic stroke. The device is used to remove blood clots and restore blood flow to the brain .
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Mechanical thrombectomy for acute ischemic stroke in a low- and middle-income country: primary outcomes from the GRASSROOT Trial.
Yavagal DR, Gaikwad SB, Vibha D, Narayan SK, et al · · 2025 · PMID 41371775 · DOI 10.1136/jnis-2025-024470 -
Late break abstract - 2024
· 2024
Verify or expand the search:
- PubMed search for NCT06249776
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Supernova revascularization device
Trials testing the same drug.
- NCT07335185 — Gravity Stroke System for Recanalization of Large Vessel Occlusion Strokes · NA · not yet recruiting
Other recruiting trials for Ischemic Stroke
Currently open trials in the same condition.
- NCT07509645 — Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Post · Phase 3 · recruiting
- NCT07375953 — Repeated Intravenous Thrombolysis for Ischemic Stroke Within 3.0 Hours of Onset With Tenecteplase (RITIS-TNK) · Phase 2 · recruiting
- NCT07375966 — Repeated Intravenous Thrombolysis for Ischemic Stroke With Medium to Large Vessel Occlusion Presenting Within 4.5 Hours · Phase 2 · recruiting
- NCT07491952 — Continuous Dual Aspiration Technique With Zoom System for Stroke · recruiting
- NCT07371455 — A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LWP779 in Healthy Participants · Phase 1 · recruiting
Other Gravity Medical Technology, INC trials
Trials by the same sponsor.
- NCT07335185 — Gravity Stroke System for Recanalization of Large Vessel Occlusion Strokes · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06249776 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Gravity Medical Technology, INC
- Last refreshed: 17 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06249776.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing