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NCT06242145
Clopidogrel Versus Cilostazol in Large-vessel Ischemic Stroke
Phase 3 trial testing Clopidogrel tablet in Ischemic Stroke in 580 participants. Completed in 1 August 2024.
1 July 2024
Quick facts
| Lead sponsor | Kafrelsheikh University |
|---|---|
| Phase | Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 580 |
| Start date | 1 January 2023 |
| Primary completion | 1 July 2024 |
| Estimated completion | 1 August 2024 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Clopidogrel tablet — full drug profile →
- Cilostazol 100 MG — full drug profile →
Conditions studied
- Ischemic Stroke — all drugs for Ischemic Stroke →
Sponsor
Kafrelsheikh University
Who can join
Adults 18 to 75, any sex, with Ischemic Stroke. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Along with the current clinical trial, the efficacy and safety of a 300 mg loading dose of ticagrelor administered within 24 hours of the first-ever large-vessel ischemic stroke compared to 200 mg cilostazol were assessed through NIHSS, mRS, and possible adverse effects.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Cilostazole versus clopidogrel in acute large-vessel moderate and moderate-to-severe ischemic stroke: a randomized controlled trial.
Ahmed SR, Khalil MFE, Ismaiel M, Omar TY, et al · · 2025 · cited 1× · PMID 40232632 · DOI 10.1007/s10072-025-08107-9
Verify or expand the search:
- PubMed search for NCT06242145
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Clopidogrel tablet
Trials testing the same drug.
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- NCT05553613 — Ticagrelor Versus Clopidogrel in Ischemic Stroke · Phase 3 · completed
- NCT05573958 — To Assess the Efficacy and Safety of Dual Anticoagulants i.e. Rivaroxaban Plus Aspirin and Clopidogrel Plus Aspirin in P · Phase 4 · unknown
- NCT06242132 — Clopidogrel Versus Cilostazol in Ischemic Stroke · Phase 3 · completed
Other recruiting trials for Ischemic Stroke
Currently open trials in the same condition.
- NCT07509645 — Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Post · Phase 3 · recruiting
- NCT07375953 — Repeated Intravenous Thrombolysis for Ischemic Stroke Within 3.0 Hours of Onset With Tenecteplase (RITIS-TNK) · Phase 2 · recruiting
- NCT07375966 — Repeated Intravenous Thrombolysis for Ischemic Stroke With Medium to Large Vessel Occlusion Presenting Within 4.5 Hours · Phase 2 · recruiting
- NCT07491952 — Continuous Dual Aspiration Technique With Zoom System for Stroke · recruiting
- NCT07371455 — A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LWP779 in Healthy Participants · Phase 1 · recruiting
Other Kafrelsheikh University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06242145 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Kafrelsheikh University
- Last refreshed: 20 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06242145.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing