NCT06233851 (t-BIOMAP) is a clinical trial in Mild Traumatic Brain Injury, sponsored by Pediatric Clinical Research Platform.

Who is sponsoring NCT06233851?

NCT06233851 is sponsored by Pediatric Clinical Research Platform.

What condition does NCT06233851 study?

NCT06233851 studies Mild Traumatic Brain Injury.

Is NCT06233851 still recruiting?

NCT06233851 is currently completed. Last updated 7 November 2024.

Last reviewed 2024-11-07 · How we verify

NCT06233851: t-BIOMAP

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

BLOOD BIOMARKERS in PAEDIATRIC MTBI

Completed Last updated 7 November 2024

What this trial tests

trial in Mild Traumatic Brain Injury in 600 participants. Completed in 8 July 2024.

Timeline

6 October 2020

Primary endpoint
10 June 2024

8 July 2024

Quick facts

Lead sponsor	Pediatric Clinical Research Platform
Status	Completed
Study type	OBSERVATIONAL
Enrollment	600
Start date	6 October 2020
Primary completion	10 June 2024
Estimated completion	8 July 2024
Sites	1 location across Switzerland

Conditions studied

Mild Traumatic Brain Injury — all drugs for Mild Traumatic Brain Injury →

Sponsor

Pediatric Clinical Research Platform

Who can join

Adults 0 Months to 16, any sex, with Mild Traumatic Brain Injury. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this observational study is to identify blood biomarkers that could help in the management of paediatric patients with mild TBI. The main questions it aims to answer are: 1. How can blood biomarkers reduce unnecessary CT scan and reduce the length of stay at the emergency department? 2. How can blood biomarker predict post-concussion symptoms? Participants will have a blood sample taken when they are admitted at emergency department and will receive a questionnaire describing their symptoms 14 days and 3 months after their trauma.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Management of Pediatric Mild Traumatic Brain Injury Patients: S100b, Glial Fibrillary Acidic Protein, and Heart Fatty-Acid-Binding Protein Promising Biomarkers.
Chiollaz AC, Pouillard V, Spigariol F, Romano F, et al · · 2024 · cited 5× · PMID 39071980 · DOI 10.1089/neur.2024.0027
Diagnostic potential of IL6 and other blood-based inflammatory biomarkers in mild traumatic brain injury among children.
Chiollaz AC, Pouillard V, Habre C, Seiler M, et al · · 2024 · cited 4× · PMID 39055316 · DOI 10.3389/fneur.2024.1432217
Evaluating NfL and NTproBNP as predictive biomarkers of intracranial injuries after mild traumatic brain injury in children presenting to emergency departments.
Chiollaz AC, Pouillard V, Seiler M, Habre C, et al · · 2025 · cited 1× · PMID 39949794 · DOI 10.3389/fneur.2025.1518776

Verify or expand the search:

Other recruiting trials for Mild Traumatic Brain Injury

Currently open trials in the same condition.

NCT07246993 — Targeting Neuroplasticity for Persistent Post-Concussive Cognitive Symptoms · NA · recruiting
NCT07356167 — Passive Neurosensory Reintegration Training as a Tool to Augment Mild Traumatic Brain Injury · NA · recruiting
NCT07097792 — Concussion Recovery and Support Program · NA · recruiting
NCT06956417 — REhabilitation of MEMory Symptoms After BRain Concussion · NA · recruiting
NCT06217575 — Brain Research Assessing Impacts of Neurophysiological Processing Speed Training in Veterans · NA · recruiting

Other Pediatric Clinical Research Platform trials

Trials by the same sponsor.

NCT04464603 — Impact of a mHealth Supportive Tool on Cardiopulmonary Resuscitation' Situational Awareness · NA · not yet recruiting
NCT05557331 — Effectiveness of a Mobile App in Reducing Therapeutic TAT in an Emergency Department · NA · recruiting
NCT06373939 — Performance and Safety of the Pneumoscope Device in Adults and Children · NA · recruiting
NCT05318599 — Deep Learning Diagnostic and Risk-stratification for IPF and COPD · recruiting
NCT05764850 — Mechanisms of Type 1 Diabetes Endophenotypes · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06233851 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Pediatric Clinical Research Platform
Last refreshed: 7 November 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06233851.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing