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NCT06229886
Effect of PEEP on TRJV in Mechanically Intubated Pediatric Patients
NA trial testing Application of positive-end-expiratory pressure in Tricuspid Regurgitation in 20 participants. Completed in 21 September 2024.
1 April 2024
Quick facts
| Lead sponsor | Northwell Health |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 20 |
| Start date | 6 December 2023 |
| Primary completion | 1 April 2024 |
| Estimated completion | 21 September 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Application of positive-end-expiratory pressure
Conditions studied
- Tricuspid Regurgitation — all drugs for Tricuspid Regurgitation →
- Mechanical Ventilation Pressure High — all drugs for Mechanical Ventilation Pressure High →
- Pediatric Respiratory Diseases — all drugs for Pediatric Respiratory Diseases →
Sponsor
Northwell Health — full company profile →
Who can join
Adults 3 Months to 18, any sex, with Tricuspid Regurgitation or Mechanical Ventilation Pressure High. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Prospective observational cohort study within the Pediatric Intensive Care Unit (PICU). We will perform point-of-care-ultrasound (POCUS) to quantify tricuspid regurgitant jet velocity (TRJV) on mechanically ventilated (MV) children. Mechanically ventilated (MV) children approaching extubation as per the discretion of the PICU clinical team will undergo a positive end expiratory pressure (PEEP) titration protocol in a safe and timely manner in the PICU. During this PEEP titration, POCUS will be performed by a pediatric intensivist and interpreted by a pediatric cardiologist. Medical demographics will be collected from the electronic medical record and recorded.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06229886
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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Other Northwell Health trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06229886 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Northwell Health
- Last refreshed: 26 September 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06229886.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing