NCT06229470 (Neural Panel) is a NA clinical trial of Evoke Spinal Cord Stimulation (SCS) System in Chronic Pain, sponsored by Saluda Medical Pty Ltd.

Who is sponsoring NCT06229470?

NCT06229470 is sponsored by Saluda Medical Pty Ltd.

What drugs are being tested in NCT06229470?

Interventions in NCT06229470: Evoke Spinal Cord Stimulation (SCS) System.

What condition does NCT06229470 study?

NCT06229470 studies Chronic Pain.

Is NCT06229470 still recruiting?

NCT06229470 is currently active, enrolled. Last updated 30 March 2026.

Last reviewed 2026-03-30 · How we verify

NCT06229470: Neural Panel

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Clinical Utility of Neurophysiological Measurements of ECAP-controlled Closed-loop SCS to Guide Treatment of Chronic Pain

Active, enrolled NA Last updated 30 March 2026

What this trial tests

NA trial testing Evoke Spinal Cord Stimulation (SCS) System in Chronic Pain in 250 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

8 March 2024

Primary endpoint
28 February 2027

28 February 2027

Quick facts

Lead sponsor	Saluda Medical Pty Ltd
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	250
Start date	8 March 2024
Primary completion	28 February 2027
Estimated completion	28 February 2027
Sites	25 locations across United States

Drugs / interventions tested

Evoke Spinal Cord Stimulation (SCS) System

Conditions studied

Chronic Pain — all drugs for Chronic Pain →

Sponsor

Saluda Medical Pty Ltd — full company profile →

Who can join

18 and older, any sex, with Chronic Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to evaluate the clinical utility of neurophysiological measurements of ECAP-controlled closed-loop SCS (i.e., neural panel metrics) to guide treatment of chronic pain of the trunk and/or limbs.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

ECAP-Controlled Closed-Loop Spinal Cord Stimulation for Chronic Nonsurgical Refractory Back Pain: Subgroup Analysis From Two Prospective Multicenter Clinical Trials.
Hunter CW, Raskin JS, Mekhail NA, Petersen EA, et al · · 2025 · cited 1× · PMID 40590186 · DOI 10.1097/brs.0000000000005445
Next-Generation SCS Programming Platform: Enhancing ECAP Fidelity and Objectivity to Improve Patient Experience.
Parker DJ, Antony AB, Smith GL, Goree JH, et al · · 2026 · PMID 41505067 · DOI 10.1007/s40122-025-00808-5
First Objective Evidence Characterizing Differences in Cervical and Thoracic Spinal Cord Neurophysiology Using ECAP-Controlled Closed-Loop Technology.
Goree JH, Nijhuis H, Smith GL, Petersen EA, et al · · 2025 · PMID 41066061 · DOI 10.1007/s40122-025-00782-y

Verify or expand the search:

Other trials of Evoke Spinal Cord Stimulation (SCS) System

Trials testing the same drug.

NCT05272137 — Evoke Data Collection Study Germany · completed
NCT04662905 — Novel Treatment Delivery of ECAP-controlled Closed-loop SCS for Chronic Pain · NA · recruiting
NCT04319887 — ECAP-controlled, Closed-loop Stimulation to Treat Chronic Trunk and/or Limb Pain (ECAP) · NA · completed
NCT04627974 — Long-term Effectiveness, Safety, and Performance of the Evoke Closed-Loop SCS System to Treat Patients With Chronic Pain · active not recruiting

Other recruiting trials for Chronic Pain

Currently open trials in the same condition.

NCT07491549 — The Effect of Pain Education Group Therapy and Its Impact on Chronic Pain, Kinesiophobia, and Physical Activity · NA · recruiting
NCT07425691 — SPACE for Youth With Chronic Pain · recruiting
NCT07103135 — Optimizing Accelerated TMS for Chronic Pain With Thompson Sampling · Phase 1 · recruiting
NCT06219408 — CIH Stepped Care for Co-occurring Chronic Pain and PTSD · NA · recruiting
NCT07270406 — Healthy Behaviors for Insomnia Prevention in People With HIV and Ongoing Pain · NA · recruiting

Other Saluda Medical Pty Ltd trials

Trials by the same sponsor.

NCT06057480 — APM in the Evoke SCS System to Program Patients With Chronic Pain of the Trunk and/or Limbs · NA · completed
NCT05272137 — Evoke Data Collection Study Germany · completed
NCT04662905 — Novel Treatment Delivery of ECAP-controlled Closed-loop SCS for Chronic Pain · NA · recruiting
NCT04319887 — ECAP-controlled, Closed-loop Stimulation to Treat Chronic Trunk and/or Limb Pain (ECAP) · NA · completed
NCT04627974 — Long-term Effectiveness, Safety, and Performance of the Evoke Closed-Loop SCS System to Treat Patients With Chronic Pain · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06229470 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Saluda Medical Pty Ltd
Last refreshed: 30 March 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06229470.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing