Last reviewed · How we verify
NCT06226116: BIC
COMPARATIVE STUDY OF BONE IMPLANT CONTACT (BIC) ON NEW BONE REGENERATED WITH AUTOGENOUS DENTIN AND NATIVE BONE
NA trial testing socket preservation in Bone Resorption in 27 participants. Status unknown.
1 August 2023
Quick facts
| Lead sponsor | Universidad de León |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 27 |
| Start date | 1 January 2018 |
| Primary completion | 1 August 2023 |
| Estimated completion | 1 December 2024 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- socket preservation
- placement of experimental implants
- histological sample collection
Conditions studied
- Bone Resorption — all drugs for Bone Resorption →
- Bone Regeneration — all drugs for Bone Regeneration →
Sponsor
Universidad de León
Who can join
18 and older, any sex, with Bone Resorption or Bone Regeneration. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The healing process after tooth removal involves bone remodelling which implies some loss of alveolar bone volume.Among materials proposed for minimising this remodelling and preserving the bone, autologous dental tissue is a promising option, but more data are needed. In this context, the investigator evaluated size and density changes using cone beam computed tomography in autologous dental material (ADM)-preserved sockets compared to controls,and assessed biological responses by histological analysis of bone implant contact (BIC) an Area density (AA) using experimental Bioetch® surface implant.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Use of autologous tooth-derived material as a graft in the post-extraction socket. Split-mouth study with radiological and histological analysis.
López Sacristán H, Del Canto Pingarrón M, Alobera Gracia MA, de Elío Oliveros J, et al · · 2024 · cited 7× · PMID 39044178 · DOI 10.1186/s12903-024-04576-0
Verify or expand the search:
- PubMed search for NCT06226116
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06226116 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidad de León
- Last refreshed: 26 January 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06226116.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing