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Acceptability and Nutritional Impact of Double-fortified Salt Containing Iodine and Folic Acid (DFS-IoFA-2)
The overarching objective of this two-phase project is to assess the effects of fortifying iodized salt with folic acid on improving women's folate status. Folate insufficiency is the primary risk factor for neural tube defects (NTDs), which are highly prevalent in Ethiopia. The purposes of Phase 2 of the project, described herein, are to complete a community-based, randomized, dose-response intervention trial of edible salt fortified with just iodine or iodine and one of two levels of folic acid among non-pregnant women of reproductive age (WRA), We will assess the effects of the intervention on women's discretionary salt intakes, markers of folate and iodine status, and incidence of any adverse events.
Details
| Lead sponsor | University of California, Davis |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 360 |
| Start date | Thu Apr 25 2024 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Mon Dec 16 2024 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Folate Deficiency
- Iodine Deficiency
- Anemia Macrocytic
- Anemia Deficiency
- Salt Intake
- Vitamin B 12 Deficiency
Interventions
- Iodized salt
- Experimental: Iodized salt with lower-dose folic acid fortification
- Experimental: Iodized salt with higher-dose folic acid fortification
Countries
Ethiopia