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NCT06223373: BFR

Blood Flow Restriction Therapy Following Acute Shoulder Injury Patients

Terminated NA Results posted Last updated 4 November 2025
What this trial tests

NA trial testing Blood Flow Restriction in Shoulder Injury in 3 participants. Terminated before completion.

Timeline
13 April 2024
Primary endpoint
18 October 2024
18 October 2024

Quick facts

Lead sponsorWake Forest University Health Sciences
PhaseNA
StatusTerminated
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposesupportive care
Enrollment3
Start date13 April 2024
Primary completion18 October 2024
Estimated completion18 October 2024
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

Wake Forest University Health Sciences

Who can join

Adults 18 to 55, any sex, with Shoulder Injury. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Shoulder Muscle Strength Analysis: External Rotation (ER) Peak Torque Average (60 Degrees/Second) Primary · Baseline

measuring shoulder strength in injured and non-injured arms for both study groups using a Biodex testing machine - Low Score indicates low torque/strength, high score indicates high torque/strength

GroupValue95% CI
Blood Flow Restriction (BFR)28.6± 0
"Sham" Blood Flow Restriction (BFR)13.1± 8.3
Shoulder Muscle Strength Analysis: External Rotation (ER) Peak Torque Average (60 Degrees/Second) Primary · Week 6

measuring shoulder strength in injured and non-injured arms for both study groups using a Biodex testing machine - Low Score indicates low torque/strength, high score indicates high torque/strength

GroupValue95% CI
Blood Flow Restriction (BFR)23.2± 0
"Sham" Blood Flow Restriction (BFR)19.2± 0
Shoulder Muscle Strength Analysis: External Rotation (ER) Peak Torque Average (180 Degrees/Second) Primary · Baseline

Low Score indicates low torque/strength, high score indicates high torque/strength

GroupValue95% CI
Blood Flow Restriction (BFR)19.0± 0
"Sham" Blood Flow Restriction (BFR)11.1± 5.9
Shoulder Muscle Strength Analysis: External Rotation (ER) Peak Torque Average (180 Degrees/Second) Primary · Week 6

Low Score indicates low torque/strength, high score indicates high torque/strength

GroupValue95% CI
Blood Flow Restriction (BFR)16.6± 0
"Sham" Blood Flow Restriction (BFR)13.9± 0
Shoulder Muscle Strength Analysis: External Rotation (ER) Peak Torque Average (300 Degrees/Second) Primary · Baseline

Low Score indicates low torque/strength, high score indicates high torque/strength

GroupValue95% CI
Blood Flow Restriction (BFR)14.4± 0
"Sham" Blood Flow Restriction (BFR)7.0± 0.28
Shoulder Muscle Strength Analysis: External Rotation (ER) Peak Torque Average (300 Degrees/Second) Primary · Week 6

Low Score indicates low torque/strength, high score indicates high torque/strength

GroupValue95% CI
Blood Flow Restriction (BFR)11.2± 0
"Sham" Blood Flow Restriction (BFR)13.6± 0
Shoulder Muscle Strength Analysis: Internal Rotation (IR) Peak Torque Average (60 Degrees/Second) Primary · Baseline

Low Score indicates low torque/strength, high score indicates high torque/strength

GroupValue95% CI
Blood Flow Restriction (BFR)23.2± 0
"Sham" Blood Flow Restriction (BFR)11.0± 9.5
Shoulder Muscle Strength Analysis: Internal Rotation (IR) Peak Torque Average (60 Degrees/Second) Primary · Week 6

Low Score indicates low torque/strength, high score indicates high torque/strength

GroupValue95% CI
Blood Flow Restriction (BFR)27.2± 0
"Sham" Blood Flow Restriction (BFR)9.9± 0
Shoulder Muscle Strength Analysis: Internal Rotation (IR) Peak Torque Average (180 Degrees/Second) Primary · Baseline

Low Score indicates low torque/strength, high score indicates high torque/strength

GroupValue95% CI
Blood Flow Restriction (BFR)23.5± 0
"Sham" Blood Flow Restriction (BFR)15.6± 7.8
Shoulder Muscle Strength Analysis: Internal Rotation (IR) Peak Torque Average (180 Degrees/Second) Primary · Week 6

Low Score indicates low torque/strength, high score indicates high torque/strength

GroupValue95% CI
Blood Flow Restriction (BFR)26.7± 0
"Sham" Blood Flow Restriction (BFR)7.6± 0
Shoulder Muscle Strength Analysis: Internal Rotation (IR) Peak Torque Average (300 Degrees/Second) Primary · Baseline

Low Score indicates low torque/strength, high score indicates high torque/strength

GroupValue95% CI
Blood Flow Restriction (BFR)23.5± 0
"Sham" Blood Flow Restriction (BFR)14.5± 2.3
Shoulder Muscle Strength Analysis: Internal Rotation (IR) Peak Torque Average (300 Degrees/Second) Primary · Week 6

Low Score indicates low torque/strength, high score indicates high torque/strength

GroupValue95% CI
Blood Flow Restriction (BFR)26.6± 0
"Sham" Blood Flow Restriction (BFR)6.6± 0

Sponsor's own description

Atrophy and weakness of the shoulder are a common problem following treatment of a number of shoulder and elbow pathologies. Even with relatively short periods of reduced activity, the magnitude of muscle loss can be quite substantial.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Blood Flow Restriction

Trials testing the same drug.

Other recruiting trials for Shoulder Injury

Currently open trials in the same condition.

Other Wake Forest University Health Sciences trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06223373.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing