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NCT06223035
Myokine Identification Following Acute Exercise
NA trial testing Exercise in Adiposity in 12 participants. Completed in 9 August 2024.
9 August 2024
Quick facts
| Lead sponsor | Rockefeller University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 12 |
| Start date | 18 April 2024 |
| Primary completion | 9 August 2024 |
| Estimated completion | 9 August 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Exercise
Conditions studied
- Adiposity — all drugs for Adiposity →
Sponsor
Rockefeller University
Who can join
Adults 18 to 45, any sex, with Adiposity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Exercise stimulates a cascade of responses within the human body. For example, exercise results in the release of proteins into the circulation which communicate with cells and organs throughout the body. In fact, recent human research identified more than 600 proteins are released into the blood circulation following short-term exercise, many of which are predicted to come from the skeletal muscle and target the fat tissue. However, identification of these muscle-secreted proteins and their target tissue (i.e. fat tissue) remains extremely challenging. This challenge is because tissue needs to be collected from multiple sites (skeletal muscle and fat) and at multiple timepoints (before and after exercise). This study seeks to address these challenges through the collection of fat and blood both before and after short-term exercise followed by protein detection (of the blood) and gene expression (of the fat tissue).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Exercise intensity modulates the human plasma secretome and interorgan communication
Olsen L, Botella J, Barrows D, Romero E, et al · · 2025 · DOI 10.1101/2025.10.22.683699
Verify or expand the search:
- PubMed search for NCT06223035
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Exercise
Trials testing the same drug.
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- NCT07007858 — Effects of High-Velocity Passive Stretch on Spasticity, Function, and Muscle Structure in Spastic CP Children · NA · enrolling by invitation
- NCT07589725 — Mulligan Mobilization in Lateral Elbow Tendinopathy · NA · not yet recruiting
- NCT07524400 — Effects of Physical Exercise Combined With Transcranial Direct Current Stimulation in Parkinson's Disease · NA · recruiting
- NCT06627569 — Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans · NA · not yet recruiting
Other recruiting trials for Adiposity
Currently open trials in the same condition.
- NCT06532747 — Redefining BMI: The Body, Mind, and Inflammation Trial · NA · recruiting
- NCT07103343 — MOVI-OLE! [Open Learning Environments] · NA · active not recruiting
- NCT06264882 — Cardiometabolic Consequences of the Loss of Ovarian Function · Phase 4 · recruiting
- NCT06208345 — Early Life Intervention in Pediatrics Supported by E-health · NA · recruiting
- NCT06129110 — Effect of Weight Loss on Intermuscular Adipose Tissue (IMAT) Signaling · NA · recruiting
Other Rockefeller University trials
Trials by the same sponsor.
- NCT06887543 — The Impact of Time Restricted Eating on Type 2 Diabetes · NA · terminated
- NCT06424132 — Thermogenic Silencer Regulatory Factors in Humans · NA · active not recruiting
- NCT06146218 — Compassion-Based Resiliency Training (CBRT) Intervention on Racism-based Stress · NA · completed
- NCT05856890 — HepB mAb19 in Individuals With Chronic Hepatitis B Infection · Phase 1 · recruiting
- NCT05834036 — Effect of Antibiotics on Enteric Neurons and Glia · Phase 4 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06223035 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rockefeller University
- Last refreshed: 10 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06223035.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing