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NCT06218758
Prediction Model for PPCs in Patients Undergoing Lung Transplantation Using Machine Learning
trial testing General anesthesia in Lung Transplantation in 214 participants. Completed in 30 June 2025.
30 June 2025
Quick facts
| Lead sponsor | Pusan National University Yangsan Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 214 |
| Start date | 22 January 2024 |
| Primary completion | 30 June 2025 |
| Estimated completion | 30 June 2025 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- General anesthesia — full drug profile →
Conditions studied
- Lung Transplantation — all drugs for Lung Transplantation →
Sponsor
Pusan National University Yangsan Hospital
Who can join
18 and older, any sex, with Lung Transplantation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Since the first human lung transplantation in 1963, significant advancements in immunosuppressive agents from the mid-1990s have greatly improved the quantity and quality of such procedures. In 2004, a total of 1,815 lung transplantations were globally reported. Patients undergoing this procedure are typically elderly and experience not only impaired lung function but also overall health instability. Despite successful outcomes, postoperative pulmonary complications (PPCs) can lead to serious consequences, including deterioration and fatality. PPCs resulting from lung transplantation may lead to prolonged hospitalization, increased complications, and the need for additional treatment. Various factors, such as age, smoking, pre-existing lung diseases, immunosuppressive drug use, diabetes, hypertension, infections, allergies, and immune disorders, are associated with the development of PPCs. The retrospective analysis of medical records from adult patients who underwent lung transplantation aims to investigate patient characteristics, anesthesia methods, intraoperative tests, and the occurrence of PPCs, with the ultimate goal of analyzing the incidence and risk factors of postoperative respiratory complications and developing a predictive model through machine learning.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06218758
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Related trials
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Other recruiting trials for Lung Transplantation
Currently open trials in the same condition.
- NCT07479511 — Adaptation of Lung Transplant Recipients at Extreme Altitude · active not recruiting
- NCT06853223 — This Study is Assessing the Safety and Efficacy of Immune Inhibition as a Treatment to Prevent Primary Graft Dysfunction · Phase 2 · recruiting
- NCT06868823 — Prospective Observational Pilot Study of LMWH Versus UFH as ECMO Anticoagulation in Lung Transplantation · recruiting
- NCT07316829 — TRAnscriptional Profile of Peripheral Blood Cells in Patient With Chronic Kidney and Lung Rejection: Correlation With Re · active not recruiting
- NCT06327945 — Transplanting Lungs From Uncontrolled Donation After Circulatory Death · NA · recruiting
Other Pusan National University Yangsan Hospital trials
Trials by the same sponsor.
- NCT07511634 — Comparison of Sevoflurane and Desflurane on ANI in Patients Undergoing General Anesthesia: a Prospective Randomized Cont · NA · not yet recruiting
- NCT07324226 — Effects of Combined Heat Application and Acupressure to the Carotid Artery Region on Cerebral Blood Flow in Healthy Adul · NA · recruiting
- NCT07334327 — Extracorporeal Blood Purification Using Oxiris for Septic Shock (EXPLORE Study) · NA · not yet recruiting
- NCT07323823 — The Effect of PBM on the Electrical Activity of the Brain in Stroke Patients · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06218758 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Pusan National University Yangsan Hospital
- Last refreshed: 1 August 2025
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