Last reviewed · How we verify
NCT06218316
Repetitive Transcranial Magnetic Stimulation Versus Botulinum Injection on Spasticity on Children With Diplegic Cerebral Palsy
NA trial testing botulinum toxin A in Spastic Diplegic Cerebral Palsy in 75 participants. Completed in 10 August 2024.
20 January 2024
Quick facts
| Lead sponsor | MTI University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 75 |
| Start date | 15 October 2023 |
| Primary completion | 20 January 2024 |
| Estimated completion | 10 August 2024 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- botulinum toxin A — full drug profile →
- Transcranial Magnetic Stimulation — full drug profile →
- Rehabilitation Training Protocol
Conditions studied
- Spastic Diplegic Cerebral Palsy — all drugs for Spastic Diplegic Cerebral Palsy →
Sponsor
MTI University
Who can join
Adults 4 to 4, any sex, with Spastic Diplegic Cerebral Palsy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This trial will enroll 75 children with spastic diplegic cerebral palsy both matched in age, sex, degree of disability and cognitive functions with the same exclusion criteria undergoing the same physical therapy. All enrolled children will undergo routine physical therapy program and will be divided into three groups (n = 25 per group) according treatment methods. Group A: children will be given local injections of botulinum toxin type ,Group B: children will be given repetitive transcranial magnetic stimulation on the affected side; Group C: children will be given local injections of botulinum toxin type A combined with repetitive transcranial magnetic stimulation , the three groups will take physical therapy (PT) of 45 minutes duration 4 days a week for 3 months .The grade of spasticity will be assessed by using Modified Ashworth scale and M/H ratio by using EMG. The grade of motor function will assessed by using Gross Motor Function Classification System (GMFCS).
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06218316
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of botulinum toxin A
Trials testing the same drug.
- NCT05296759 — Botulinum Toxin Type A in Diabetic Peripheral Neuropathy · Phase 4 · completed
- NCT03833063 — Glabellar Botulinum Toxin Injections for the Treatment of Geriatric Depression · Phase 1 · withdrawn
- NCT03187626 — Efficacy of an Intra-articular Injection of Botulinum Toxin A Associated With Splinting for Base-of-thumb Osteoarthritis · Phase 2, PHASE3 · completed
- NCT03816046 — Hyperhydrosis Treatment Using Botulinum Toxin · Phase 4 · completed
- NCT05618470 — Wumeiwan Jiawei Fang Use in Patients With Blepharospasm · Phase 2, PHASE3 · unknown
Other MTI University trials
Trials by the same sponsor.
- NCT07510399 — Effect of Extracorporeal Radial Shock Wave Ibuprofen Phonophoresis on Subacromial Space in Patients With Impingement Syn · NA · not yet recruiting
- NCT07394595 — Upper Versus Lower Limb Cycling Exercise With Electrical Muscle Stimulation on Perceptual Responses, Energy Feelings · NA · completed
- NCT07196956 — Effect of Electromagnetic Field Therapy on Balance and Gait in Paraparetic Patients · NA · not yet recruiting
- NCT07334847 — Anterior Foot Wedge With Neuromuscular Training for Balance in Parkinson's Disease · NA · not yet recruiting
- NCT07365748 — Evaluation of Bacterial Contamination and Antimicrobial Efficacy on Charcoal-Infused vs, Standard Nylon Toothbrush Brist · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06218316 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by MTI University
- Last refreshed: 19 September 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06218316.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing