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NCT06211309
Evaluation of Anti-plaque and Anti-inflammatory Effects of Green Tea and Salvadora Persica L. in Patients With Gingivitis
Phase 2 trial testing co.mouthwas in Gingivitis in 45 participants. Status unknown.
1 May 2024
Quick facts
| Lead sponsor | University of Baghdad |
|---|---|
| Phase | Phase 2 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | prevention |
| Enrollment | 45 |
| Start date | 1 January 2024 |
| Primary completion | 1 May 2024 |
| Estimated completion | 1 July 2024 |
| Sites | 1 location across Iraq |
Drugs / interventions tested
- co.mouthwas — full drug profile →
- Kin
- Distilled water — full drug profile →
Conditions studied
- Gingivitis — all drugs for Gingivitis →
Sponsor
University of Baghdad
Who can join
Adults 15 to 55, any sex, with Gingivitis. Healthy volunteers can join.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
change in plaque index
Time frame: 0-30 days
Mean amount plaque between different comparators. Mean amount plaque between different comparators as anti-plaque agent after rinsing with different comparators using means of modified quigely hein plaque index\[ Turesky ,1970
Sponsor's own description
Gingivitis is an inflammatory condition of the gingival tissue, most commonly caused by bacterial infection.The plaque control is considered the most important preventive factor concerning caries, gingivitis, and periodontitis Mechanical means of plaque control, e.g. tooth brushing, flossing and use of other mechanical devices are the most commonly used methods. However, ideal plaque control solely by mechanical means requires a significant effort and is difficult to achieve.This has led to the introduction of chemical methods of plaque control using antimicrobial agentsMore specifically, chemotherapeutic agents with antimicrobial properties, such as 0.12% chlorhexidine (CHX).chx has side effects encourage the need to develop alternative mouthwashes with similar efficacy but without these issues.hence the mouthwash enriched with a combination of aqueous extracts of Salvadora persica L. and green tea used as a substitution to CHX with minimal side effects .The objective of this study was to investigate the efficacy of the combination of Gt aqueous extract and Sp aqueous extract in reducing plaque buildup and gingivitis for 4 weeks duration.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06211309
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Related trials
Other recruiting trials for Gingivitis
Currently open trials in the same condition.
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- NCT07164989 — Motivational Interviewing to Improve Oral Hygiene in Adolescent Orthodontic Patients · NA · active not recruiting
- NCT07530978 — ORAL HYGIENE, PERIODONTAL STATUS AND QUALITY OF LIFE · recruiting
Other University of Baghdad trials
Trials by the same sponsor.
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- NCT07460089 — Premature Infant Oral Motor Intervention vs. Pacifier for Oral Feeding Transition in Preterm Infants · NA · not yet recruiting
- NCT07350343 — The Predictability of Directly Printed Versus Thermoformed Clear Aligners · NA · enrolling by invitation
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06211309 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Baghdad
- Last refreshed: 28 January 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06211309.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing