Last reviewed · How we verify
Efficacy of Intranasal Povidone Iodine Swab Versus Oral Antibiotic Prophylaxis to Prevent Surgical Site Infections in Patients Undergoing Mohs Micrographic Surgery
The purpose of this study is to compare surgical site infection rates for patients treated with Mohs micrographic surgery after bilateral nasal swab with povidone iodine versus standard treatment including the use of a standardized oral antibiotic prophylaxis protocol.
Details
| Lead sponsor | Mayo Clinic |
|---|---|
| Phase | NA |
| Status | WITHDRAWN |
| Start date | 2024-09-01 |
| Completion | 2030-05 |
Conditions
- Skin Cancer
- Skin Cancer Face
- Malignant Cutaneous Adnexal Neoplasm
Interventions
- Povidone-Iodine Swabs
- Staphylococcus nasal swab
- Antibiotic
Primary outcomes
- Effectiveness of nasal decolonization with povidone-iodine versus a standardized oral antibiotic prophylaxis protocol to prevent surgical site infection (SSI) — 30 days after MMS
Effectiveness of nasal decolonization will be assessed based on the presence of SSI within 30 days after Mohs micrographic surgery (MMS). SSI is defined by the United States Centers for Disease Control and Prevention as infection of the cutaneous and subcutaneous tissue occurring within 30 days of surgery. Rates of SSI for both treatment arms will be reported.