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NCT06201455: ECO
Evaluation of Phacogoniotomy in Medically-controlled POAG
NA trial testing PEI+GT in Glaucoma, Open-Angle in 100 participants. Currently enrolling.
30 September 2026
Quick facts
| Lead sponsor | Sun Yat-sen University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 100 |
| Start date | 28 September 2023 |
| Primary completion | 30 September 2026 |
| Estimated completion | 31 December 2029 |
| Sites | 1 location across China |
Drugs / interventions tested
- PEI+GT
- PEI+MED
Conditions studied
- Glaucoma, Open-Angle — all drugs for Glaucoma, Open-Angle →
- Cataract Complicated — all drugs for Cataract Complicated →
- Goniotomy — all drugs for Goniotomy →
Sponsor
Sun Yat-sen University
Who can join
Adults 40 to 85, any sex, with Glaucoma, Open-Angle or Cataract Complicated. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this multicenter non-inferiority randomized controlled trial is to compare the efficacy of phacoemulsification with intraocular lens implantation (PEI) combined with goniotomy (GT) and PEI combined with medical therapy (MED) in the treatment of medically-controlled primary open-angle glaucoma (POAG) with cataract. The main questions it aims to answer are: * Whether the PEI+GT was non-inferior to PEI+MED with regard to the intraocular pressure lowering effect in medically-controlled POAG. * Whether the PEI+GT has value of health economics. Participants will be randomized to receive either PEI+GT or PEI+MED, and followed up with a 1-year period as a primary outcome.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Intraocular pressure is a promising target for myopia control.
Wang P, Kong K, Jiang J, Jiang J, et al · · 2025 · cited 1× · PMID 40380302 · DOI 10.1186/s12967-025-06546-8
Verify or expand the search:
- PubMed search for NCT06201455
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Glaucoma, Open-Angle
Currently open trials in the same condition.
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- NCT05405868 — Nicotinamide in Glaucoma (NAMinG): A Randomised, Placebo-controlled, Multi-centre, Phase III Trial · Phase 3 · recruiting
- NCT05710198 — Efficacy of Citicoline Eye Drops 2% on Visual Field Preservation in Patients With Open Angle Glaucoma · Phase 3 · recruiting
- NCT06058598 — Exercise Training in Patients With Glaucoma · NA · active not recruiting
Other Sun Yat-sen University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06201455 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sun Yat-sen University
- Last refreshed: 11 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06201455.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing