Last reviewed · How we verify
NCT06197321: VACC
Non-invasive Prediction of Fluid and Noradrenaline Responsiveness Using the Carotid Wave Intensity.
trial in Shock in 120 participants. Completed in 31 December 2024.
30 November 2024
Quick facts
| Lead sponsor | Catharina Ziekenhuis Eindhoven |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 120 |
| Start date | 15 January 2024 |
| Primary completion | 30 November 2024 |
| Estimated completion | 31 December 2024 |
| Sites | 1 location across Netherlands |
Conditions studied
- Shock — all drugs for Shock →
- Aortic Valve Disease — all drugs for Aortic Valve Disease →
- Coronary Artery Disease — all drugs for Coronary Artery Disease →
- Mitral Valve Disease — all drugs for Mitral Valve Disease →
Sponsor
Catharina Ziekenhuis Eindhoven — full company profile →
Who can join
18 and older, any sex, with Shock or Aortic Valve Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this observational study is to study a new method to compute ventricular-arterial coupling (VAC) in adult intensive care patients after cardiac surgery. VAC is a metric that describes the interaction between the heart and the arterial system. The new method of measuring VAC uses carotid ultrasound measurements. The main questions this study aims to answer are: * Can VAC measured using carotid ultrasound predict the hemodynamic response to drugs? * What is the concordance of VAC measurements obtained via carotid ultrasound with VAC measurements obtained via the standard, single-beat method? Measurements will be performed in the operating room and at the ICU.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06197321
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Shock
Currently open trials in the same condition.
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- NCT07009665 — Fluid Management and Individualized Resuscitation in Sepsis · NA · recruiting
- NCT06713668 — Augmented Pacing for Shock in the Cardiac Intensive Care Unit · NA · recruiting
- NCT06930235 — Effectiveness of Midodrine as an Adjuvant to Norepinephrine in Weaning Critically Ill Patients From Vasopressors · NA · recruiting
- NCT06920173 — Pulse Study: Peripheral Use of Low-dose Vasopressors for Safety and Efficacy in the Intensive Care Unit · Phase 2 · recruiting
Other Catharina Ziekenhuis Eindhoven trials
Trials by the same sponsor.
- NCT07314138 — Multivessel Minimally Invasive Coronary Bypass Grafting as HYBRID Revascularization Versus Conventional Off-pump Coronar · NA · not yet recruiting
- NCT06768060 — Mindfulness-based Intervention Prior to External Cephalic Version · NA · recruiting
- NCT06574867 — Evaluation of the viQtor Monitoring Solution on Surgical Wards · recruiting
- NCT06374836 — The Contractile Response of the Thoracic Aorta to Vasoactive Substances · completed
- NCT06401291 — Transcutaneous Electrical Nerve Stimulation in Patients With Angina and Non-Obstructive Coronary Arteries · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06197321 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Catharina Ziekenhuis Eindhoven
- Last refreshed: 18 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06197321.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing