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NCT06195423: SOAR
Stopping OsteoARthritis After an ACL Tear
NA trial testing Stop OsteoARthritis (SOAR) program in Knee Injuries in 210 participants. Currently enrolling.
30 December 2026
Quick facts
| Lead sponsor | University of British Columbia |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 210 |
| Start date | 1 May 2024 |
| Primary completion | 30 December 2026 |
| Estimated completion | 30 December 2028 |
| Sites | 2 locations across Canada |
Drugs / interventions tested
- Stop OsteoARthritis (SOAR) program
- Living Well after ACLR program
Conditions studied
- Knee Injuries — all drugs for Knee Injuries →
- Anterior Cruciate Ligament Rupture — all drugs for Anterior Cruciate Ligament Rupture →
- Osteoarthritis, Knee — all drugs for Osteoarthritis, Knee →
Sponsor
University of British Columbia
Who can join
Adults 16 to 35, any sex, with Knee Injuries or Anterior Cruciate Ligament Rupture. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
By 2040, 25% of Canadians will have osteoarthritis, a disabling joint condition. Most people think osteoarthritis only affects older adults, but 50% of the 700,000 Canadian youth who hurt their knee playing sports annually will develop osteoarthritis by 40 years of age. These young people with old knees face knee pain and disability for much of their adult lives, interfering with parenting, work, and recreation. Yet, most do not know about osteoarthritis or how to reduce their risk. In this clinical trial, people who have torn the Anterior Cruciate ligament in their knee and had reconstruction surgery 9-36 months previously will be randomized to receive either a 6-month virtual education and exercise therapy program called Stop OsteoARthritis (SOAR) or a minimal intervention control program. Researchers will test if those who received the SOAR program have larger gains in knee health, including pain, symptoms, function, and quality of life at 6, 12, and 24 months. Researchers will also use MRIs (baseline and 24 months) to assess how the SOAR program influences knee cartilage degeneration and its cost-effectiveness.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Digital education and exercise therapy versus minimal intervention for young people at high risk of early onset knee osteoarthritis after ACL reconstruction: a study protocol for the Stop OsteoARthritis (SOAR) randomized controlled trial.
Whittaker JL, Cammalleri A, Archibald C, Brooks-Hill A, et al · · 2025 · cited 1× · PMID 40542399 · DOI 10.1186/s13063-025-08896-6 -
A roadmap for developing a program to self-manage post-traumatic knee osteoarthritis risk.
Whittaker JL, Hoens AM, Archibald C, Hunt MA, et al · · 2026 · PMID 42254335 · DOI 10.1016/j.ocarto.2026.100822
Verify or expand the search:
- PubMed search for NCT06195423
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Knee Injuries
Currently open trials in the same condition.
- NCT07300098 — Epidemiological Evaluation of Knee Injuries in Children Admitted to Assiut University Hospitals From 2022 to 2025. · active not recruiting
- NCT07201597 — Correlation Between Psychological Readiness, Knee Function, and Isokinetic Performance After Anterior Cruciate Ligament · recruiting
- NCT06541756 — Fibrine Clot-augmented Repair of Longitudinal Meniscus Tears · NA · recruiting
- NCT06442319 — The Efficiency and Safety of PRP Treatment After Anterior Cruciate Ligament Reconstruction. · NA · recruiting
- NCT06320925 — SportsPro: Post-Market Clinical Follow Up Study · recruiting
Other University of British Columbia trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06195423 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of British Columbia
- Last refreshed: 10 May 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06195423.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing